23580-81-6

Basic information

• Product Name: 1,3-di(pyridin-2-yl)propan-2-one
• CAS NO: 23580-81-6
• Molecular Formula: C₁₃H₁₂N₂O
• Molecular Weight: 212.2472
• Mol File: 23580-81-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 342.5°C at 760 mmHg
• Flash Point: 165.1°C
• Density: 1.159g/cm³
• Vapor Pressure: 7.49E-05mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 1,3-di(pyridin-2-yl)propan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-di(pyridin-2-yl)propan-2-one(23580-81-6)
• EPA Substance Registry System: 1,3-di(pyridin-2-yl)propan-2-one(23580-81-6)

Safety Data

• Hazardous Substances Data: 23580-81-6(Hazardous Substances Data)

Usage

Synonyms

β-di(pyridin-2-yl)propanone

Appearance

Yellow crystalline solid

Usage

Building block in organic synthesis and pharmaceutical research

Applications

Preparation of various heterocyclic compounds, potential use in new drugs and agrochemicals development

Synthesis

Reaction of acetone with two equivalents of 2-pyridinecarboxaldehyde

Product

β-diketone with pyridine substituents

Structure

Unique structure with functional groups

Versatility

Valuable and versatile intermediate in the production of various organic compounds

Upstream product

• 1749-29-7 2-pyridylmethyllithium 
• 105-58-8 Diethyl carbonate 
• 2739-97-1 pyridine-2-acetonitrile 
• 109-06-8 α-picoline 

Downstream Products

• 355860-62-7 4-nitro-2,6-di(2'-pyridyl)phenol 
• 871585-23-8 3,4-bis(4-(triisopropylsilylethynyl)phenyl)-2,5-dipyridin-2-yl-cyclopenta-2,4-dienone 
• 355860-63-8 4-amino-2,6-bis(pyridin-2-yl)phenol 

Relevant articles and documents

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Poly(phenylene-pyridyl) dendrimers: Synthesis and templating of metal nanoparticles

A new family of poly(phenylene-pyridyl) dendrimers (up to the fourth generation) with different periphery was synthesized via a divergent route by using a cascade of Diels - Alder cycloadditions. Tetra(4-ethynylphen-1-yl) methane served as a core. A new A

Syntheses and UV/Vis-spectroscopic properties of hydrophilic 2-, 3-, and 4-pyridyl-substituted solvatochromic and halochromic pyridinium N-phenolate betaine dyes as new empirical solvent polarity indicators

Syntheses and negative solvatochromism of nine new hydrophilic 2-, 3-, and 4-pyridyl-substituted pyridinium N-phenolate betaine dyes 3-11 are described. These were produced in order to obtain zwitterionic dyes better soluble in water and other aqueous media (such as binary water/solvent mixtures, aqueous ionophore solutions) than the rather hydrophobic standard betaine dyes 1 and 2, which have been used to establish an empirical scale of solvent polarity, called the ET(30) scale. Betaine dye 8, in which three of the peripheral phenyl groups of 1 are replaced by two 3-pyridyl rings and one 4-pyridyl ring, proved to be particularly suitable for the determination of ET(30) values in aqueous media. Wiley-VCH Verlag GmbH, 2001.