23676-05-3

Basic information

• Product Name: 4-(N-MORPHOLINO)-BENZENE METHYLCARBOXYLATE
• Synonyms: RARECHEM AL BF 1130;METHYL 4-MORPHOLINOBENZENECARBOXYLATE;4-(N-MORPHOLINO)-BENZENE METHYLCARBOXYLATE;Methyl 4-morpholin-4-yl-benzoate;methyl 4-morpholinobenzoate;4-morpholinobenzoic acid methyl ester;4-(4-morpholinyl)Benzoic acid Methyl ester
• CAS NO: 23676-05-3
• Molecular Formula: C₁₂H₁₅NO₃
• Molecular Weight: 221.25
• Product Categories: pharmacetical
• Mol File: 23676-05-3.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 371.9°Cat760mmHg
• Flash Point: 178.7°C
• Appearance: /
• Density: 1.16g/cm³
• Vapor Pressure: 9.98E-06mmHg at 25°C
• Refractive Index: 1.54
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 4-(N-MORPHOLINO)-BENZENE METHYLCARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(N-MORPHOLINO)-BENZENE METHYLCARBOXYLATE(23676-05-3)
• EPA Substance Registry System: 4-(N-MORPHOLINO)-BENZENE METHYLCARBOXYLATE(23676-05-3)

Safety Data

• Hazardous Substances Data: 23676-05-3(Hazardous Substances Data)

Usage

General Description

4-(N-Morpholino)-benzene methylcarboxylate is a chemical compound used as a reagent in organic synthesis. It is derived from benzene and contains a morpholine group and a methyl ester functional group. 4-(N-MORPHOLINO)-BENZENE METHYLCARBOXYLATE is commonly used in the pharmaceutical industry for the synthesis of various drugs and pharmaceutical intermediates. It is also used in research laboratories for the preparation of diverse organic compounds. The morpholine group in this compound provides it with unique reactivity and makes it a versatile building block in organic chemistry. Overall, 4-(N-Morpholino)-benzene methylcarboxylate has a wide range of applications in both industrial and academic settings due to its synthetic utility and flexibility.

InChI:InChI=1/C12H15NO3/c1-15-12(14)10-2-4-11(5-3-10)13-6-8-16-9-7-13/h2-5H,6-9H2,1H3

Upstream product

• 110-91-8 morpholine 
• 1126-46-1 Methyl 4-chlorobenzoate 
• 41605-53-2 methyl 4-[(nonafluorobutanesulfonyl)oxy]benzoate 
• 5765-65-1 4-(benzoyloxy)morpholine 
• 619-44-3 methyl 4-iodobenzoate 
• 403-33-8 methyl 4-flurobenzoate 
• 30483-75-1 4-bromophenyl-morpholine 
• 67-56-1 methanol 
• 162848-18-2 4-(morpholin-4-yl)benzoyl chloride 
• 6297-22-9 4-carbomethoxycyclohexanone 
• 51207-43-3 methyl 4-(tosyloxy)benzoate 
• 1204-86-0 4-(4-morpholinyl)benzaldehyde 
• 7470-38-4 4-morpholin-4-yl-benzoic acid 
• 99-76-3 methyl 4-hydroxylbenzoate 

Downstream Products

• 7470-38-4 4-morpholin-4-yl-benzoic acid 
• 183557-77-9 (4-morpholin-4-yl-phenyl)-amide 
• 280556-71-0 (4-morpholinophenyl)methanol 
• 1057647-23-0 N-{2-[4-(3-oxomorpholin-4-yl)benzoylamino]benzyl}-5-chlorothiophene-2-carboxamide 
• 720720-60-5 4-(3-oxomorpholin-4-yl)benzoic acid 
• 3077-16-5 4-(4-methylphenyl)morpholine 

Relevant articles and documents

Electrochemical Cross-Dehydrogenative Aromatization Protocol for the Synthesis of Aromatic Amines

The introduction of amines onto aromatics without metal catalysts and chemical oxidants is synthetically challenging. Herein, we report the first example of an electrochemical cross-dehydrogenative aromatization (ECDA) reaction of saturated cyclohexanones and amines to construct anilines without additional metal catalysts and chemical oxidants. This reaction exhibits a broad scope of cyclohexanones including heterocyclic ketones, affording a variety of aromatic amines with various functionalities, and shows great potential in the synthesis of biologically active compounds.

Coupling of Alternating Current to Transition-Metal Catalysis: Examples of Nickel-Catalyzed Cross-Coupling

The coupling of transition-metal to photoredox catalytic cycles through single-electron transfer steps has become a powerful tool in the development of catalytic processes. In this work, we demonstrated that transition-metal catalysis can be coupled to al

Reagent and Catalyst Capsules: A Chemical Delivery System for Reaction Screening and Parallel Synthesis

Commercially available hydroxypropyl methylcellulose capsules are employed as a fast, safe, and user-friendly chemical delivery system containing all reagents (catalyst, ligand, and base) for three important transition-metal-catalyzed reactions: Buchwald-Hartwig, Suzuki-Miyaura, and metallophotoredox C-N cross-coupling reactions. This encapsulation methodology simplifies the screening of reaction conditions and the preparation of compound libraries using parallel synthesis in organic solvents or aqueous media. These reagents-containing HPMC capsules are easy to prepare, come in different sizes, and can be stored on the bench under noninert conditions.