2404-03-7Relevant articles and documents
N,N′-dichlorobis(2,4,6-trichlorophenyl)urea (CC-2): An efficient reagent for the synthesis of chemical weapons convention-related dialkyl-N,N-dialkylphosphoramidates from dialkylphosphites
Gupta, Arvind K.,Pardasani, Deepak,Gupta, Hemendra K.,Dubey, Devendra K.
, p. 879 - 882 (2007)
The present paper describes the one-pot synthesis of dialkyl N,N-dialkylphosphoramidates (DADAP) from dialkylphosphites and dialkylamines using N,N?-dichlorobis(2,4,6-trichlorophenyl)urea (CC-2) as chlorinating reagent. DADAP belong to the schedule 2.B.6 category of the Chemical Weapons Convention (CWC), as they are the important markers of the chemical warfare agent tabun and its analogues. The study was undertaken to develop the spectral database of DADAP for verification of CWC. The reported synthetic strategy can be adopted to rapidly synthesize several analogues of DADAP during official proficiency tests. CSIRO 2007.
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Savignac,P. et al.
, p. 361 - 368 (1974)
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DIALKYLAMINO GROUP TRANSFER FROM TITANIUM (IV) TO PHOSPHORYL CENTRE. STRUCTURE-REACTIVITY STUDIES
Froneman, M.,Cheney, D. L.,Modro, T. A.
, p. 273 - 281 (2007/10/02)
Reaction between phosphoryl substrates, (EtO)2P(O)X (X = H, R, OR) and dialkylaminoderivatives of Ti(IV), Ti(NR2)nCl4-n and Mn(NEt2)2 leads to the exchange of one or both EtO groups for the NR2 substituent.The reactivity of the system depends on electronic, as well as steric, effects of both substrates, and approximately correlates with the Lewis acid-base interaction between the substrates, as measured by the i.r. spectroscopy.
