24068-54-0

Basic information

• Product Name: 1-(5-Methyl-3-Isoxazolyl)Ethanone
• Synonyms: 1-(5-Methyl-3-Isoxazolyl)Ethanone;Ethanone, 1-(5-methyl-3-isoxazolyl)-;3-acetyl-5-Methylisoxazole;3-acetyl-5-Methyl-isoxazole;5-Methyl-3-acetylisoxazol;5-Methyl-3-acetyl-isoxazol;1-(5-methyl-1,2-oxazol-3-yl)ethanone
• CAS NO: 24068-54-0
• Molecular Formula: C₆H₇NO₂
• Molecular Weight: 125.13
• Mol File: 24068-54-0.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 230.057°C at 760 mmHg
• Flash Point: 92.936°C
• Appearance: /
• Density: 1.105g/cm³
• Vapor Pressure: 0.067mmHg at 25°C
• Refractive Index: 1.468
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -5.18±0.50(Predicted)
• CAS DataBase Reference: 1-(5-Methyl-3-Isoxazolyl)Ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-Methyl-3-Isoxazolyl)Ethanone(24068-54-0)
• EPA Substance Registry System: 1-(5-Methyl-3-Isoxazolyl)Ethanone(24068-54-0)

Safety Data

• Hazardous Substances Data: 24068-54-0(Hazardous Substances Data)

Usage

General Description

1-(5-Methyl-3-Isoxazolyl)Ethanone, also known as isoxazole acetone, is an organic compound with the chemical formula C7H9NO2. It is a colorless liquid with a fruity odor, and it is commonly used in the production of various pharmaceuticals and agrochemicals. This chemical is also used as a flavoring agent in the food industry. 1-(5-Methyl-3-Isoxazolyl)Ethanone is considered to be a stable compound under normal conditions, but it may react violently with strong oxidizing agents. It is important to handle this chemical with care and to follow proper safety measures when working with it.

InChI:InChI=1/C6H7NO2/c1-4-3-6(5(2)8)7-9-4/h3H,1-2H3

Upstream product

• 557-93-7 2-bromoprop-1-ene 
• 78335-65-6 pyruvohydroximoyl chloride 
• 7647-01-0 hydrogenchloride 
• 19788-35-3 methyl 5-methylisoxazole-3-carboxylate 
• 75-16-1 methylmagnesium bromide 
• 116139-26-5 3-azido-2,5-dimethylfuran 
• 57351-99-2 5-methyl-1,2-oxazole-3-carbonitrile 
• 917-64-6 methyl magnesium iodide 
• 15441-67-5 5-hydroxyhex-3-yn-2-one 
• 116139-21-0 Z-3-azido-3-hexene-2,5-dione 
• 5471-68-1 pyruvohydroximoyl chloride 
• 1439-36-7 1-triphenylphosphoranylidene-2-propanone 
• 110-13-4 2,5-hexanedione 
• 24068-55-1 1-(5-methyl-3-isoxazolyl)ethanone oxime 

Downstream Products

• 87613-38-5 N-Methyl-N'-[1-(5-methyl-isoxazol-3-yl)-eth-(E)-ylidene]-N-phenyl-hydrazine 
• 87613-35-2 1-(5-methyl-isoxazol-3-yl)-ethanone phenylhydrazone 
• 87613-36-3 N-[1-(5-Methyl-isoxazol-3-yl)-eth-(Z)-ylidene]-N'-phenyl-hydrazine 
• 3141-59-1 2-acetyl-3-oxo-butyronitrile 
• 116139-22-1 1-(3-Acetyl-2H-azirin-2-yl)-ethanone 
• 116139-25-4 N-((E)-1-tert-Butoxy-3-oxo-but-1-enyl)-acetamide 
• 119596-06-4 (S)-1-(5-Methyl-isoxazol-3-yl)-ethanol 
• 2469-99-0 Cyanoaceton 
• 1202769-66-1 2-(5-methyl-1,2-oxazol-3-yl)but-3-yn-2-ol 
• 95104-46-4 1-(5-methyl-3-isoxazolyl)ethanol 
• 75-47-8 iodoform 
• 56400-88-5 5-Methyl-3-bromacetyl-isoxazol 
• 3405-77-4 5-methylisoxazole 3-carboxylic acid 
• 24068-56-2 1-(5-methyl-isoxazol-3-yl)-ethanone (4-nitro-phenyl)-hydrazone 

Relevant articles and documents

1,4-Conjugate additions of methoxyamine and 1,1-dimethylhydrazine to hex-3-yne-2-one: A facile synthesis of functionalized isoxazole and pyrazole precursors

When hex-3-yne-2,5-dione (2) was reacted with either methoxyamine or 1,1-dimethylhydrazine, the 1,4-addition products 4 and 7 were isolated in yields of 89% and 48% respectively. Copyright Taylor & Francis, Inc.

Hydroxypurine compound and use thereof

The invention discloses a hydroxypurine compound and a use of the hydroxypurine compound as a PDE2 or TNFa inhibitor and concretely discloses a compound shown in the formula (I) and its tautomer or pharmaceutically acceptable salt.

The Boulton-Katritzky rearrangement of isocarboxazid

(Chemical Equation Presented) Isocarboxazid rearranges on heating to 5-acetonyl-2-benzyl-4-hydroxy-1,2,3-triazole in DMF at 150°C, in the ionic liquid, [bmin]HSO4- at 100°C or as a melt at 105°C. This is the first reported example of the Boulton-Katritzky rearrangement of an acyl hydrazide.