2425-54-9Relevant articles and documents
Iron-catalyzed AlkylAlkyl negishi coupling of organoaluminum reagents
Agata, Ryosuke,Kawamura, Shintaro,Isozaki, Katsuhiro,Nakamura, Masaharu
supporting information, p. 238 - 241 (2019/03/13)
The first iron-catalyzed cross-coupling reaction of alkyl halides with alkylaluminum reagents (alkylalkyl Negishi coupling) is developed using an iron/bisphosphine catalyst system. The reaction shows high functional group tolerance: various primary alkyl halides possessing a non-protected indole, carboxyl, or hydroxy group are coupled with primary alkylaluminum reagents in good yields. Potassium fluoride plays a key role to promote the reaction by generating an aluminate species, which facilitates the transmetalation between the organoaluminum and the iron catalyst.
Process for preparing alkyl chlorides
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Page/Page column 5-6, (2008/06/13)
The invention relates to a process for preparing alkyl chlorides by reacting alcohols with gaseous hydrogen chloride in the presence of a catalyst, wherein the catalyst comprises at least one compound of the structure: wherein R1 is a linear alkyl group having from 1 to 20 carbon atoms, R2, R3, and R4 is selected from a hydrogen, an alkyl, an alkenyl, an aralkyl or an alkylaryl group from 1 to 20 carbon atoms, wherein the substituents of R2, R3, and R4 are all identical, are all different or two of the substituents of R2, R3, and R4 type are identical.
REACTION OF ALKOXYHYDROPEROXIDES WITH METAL SALTS. ALKYL HALIDE PREPARATION
Cardinale, G.,Grimmelikhuysen, J. C.,Laan, J. A. M.,Lier, F. P. van,Steen, D. van der,Ward, J. P.
, p. 5971 - 5978 (2007/10/02)
A synthesis is described of alkyl chlorides by reaction of methoxy hydroperoxides, prepared from 1-alkenes by ozonisation in methanol, with ferric chloride: RCH=CH2 --> RCH(OOH)OCH3 --> R. --> RCl.Yields of 1-chlorotetradecane were about 60percent; those of other halides from 38 to 57percent.
