Welcome to LookChem.com Sign In|Join Free

CAS

  • or

243-51-6

Post Buying Request

243-51-6 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

243-51-6 Usage

General Description

11H-Indeno[1,2-b]quinoline, also known as 11H-Indenoquinoline, is a polycyclic aromatic hydrocarbon (PAH) that exhibits anti-neoplastic and anti-inflammatory properties. It has been identified as a potent inhibitor of DNA topoisomerase II, an enzyme involved in the unwinding and rewinding of DNA during replication and transcription. Additionally, it has been studied for its potential use in cancer therapy due to its ability to induce apoptosis and inhibit cell growth. However, 11H-Indenoquinoline is also considered a mutagen and a potential carcinogen, as prolonged exposure to this chemical has been linked to DNA damage and tumor formation. Therefore, its use and handling should be approached with caution and proper safety measures to minimize the risks associated with its potential hazardous effects.

Check Digit Verification of cas no

The CAS Registry Mumber 243-51-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,4 and 3 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 243-51:
(5*2)+(4*4)+(3*3)+(2*5)+(1*1)=46
46 % 10 = 6
So 243-51-6 is a valid CAS Registry Number.

243-51-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 11H-indeno[1,2-b]quinoline

1.2 Other means of identification

Product number -
Other names UPCMLD00CSUNGBOKO5

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:243-51-6 SDS

243-51-6Relevant articles and documents

Direct synthesis of ring-fused quinolines and pyridines catalyzed byNNHY-ligated manganese complexes (Y = NR2or SR)

Han, Mingyang,Lin, Qing,Liu, Qingbin,Liu, Song,Ma, Ning,Solan, Gregory A.,Sun, Wen-Hua,Wang, Zheng,Yan, Xiuli

, p. 8026 - 8036 (2021/12/27)

Four cationic manganese(i) complexes, [(fac-NNHN)Mn(CO)3]Br (Mn-1-Mn-3) and [(fac-NNHS)Mn(CO)3]Br (Mn-4) (whereNNHis a 5,6,7,8-tetrahydro-8-quinolinamine moiety), have been synthesized and evaluated as catalysts for the direct synthesis of quinolines and pyridines by the reaction of a γ-amino alcohol with a ketone or secondary alcohol;NNHS-ligatedMn-4proved the most effective of the four catalysts. The reactions proceeded well in the presence of catalyst loadings in the range 0.5-5.0 mol% and tolerated diverse functional groups such as alkyl, cycloalkyl, alkoxy, chloride and hetero-aryl. A mechanism involving acceptorless dehydrogenation coupling (ADC) has been proposed on the basis of DFT calculations and experimental evidence. Significantly, this manganese-based catalytic protocol provides a promising green and environmentally friendly route to a wide range of synthetically important substituted monocyclic, bicyclic as well as tricyclicN-heterocycles (including 50 quinoline and 26 pyridine examples) with isolated yields of up to 93%.

OLIGOAZAFLUORENE MONOMER

-

Paragraph 0234-0235; 0237, (2020/09/05)

PROBLEM TO BE SOLVED: To provide an oligoazafluorene monomer that exhibits optical properties, heat resistance, thermal stability and good solubility. SOLUTION: The oligoazafluorene monomer is represented by the general formula (1) in the figure. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT

Phosphine-Free NNN-Manganese Complex Catalyzed α-Alkylation of Ketones with Primary Alcohols and Friedl?nder Quinoline Synthesis

Barman, Milan K.,Jana, Akash,Maji, Biplab

supporting information, p. 3233 - 3238 (2018/07/31)

Herein, we report a very simple and inexpensive catalytic system based on Earth's abundant transition metal manganese and on a bench-stable phosphine-free NNN-pincer ligand for an atom-efficient α-alkylations of ketones with primary alcohols via hydrogen-autotransfer C?C bond formation protocol. The precatalyst could be generated in situ and could be activated by using catalytic amount of base under milder conditions. A range of ketones were efficiently diversified with a broad range of primary alcohols in good to excellent isolated yields. Remarkably, this catalyst could also be employed for the synthesis of quinoline derivatives using 2-aminobenzyl alcohol as an alkylating agent. The later reaction is highly benign producing only hydrogen and water as byproducts. (Figure presented.).

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 243-51-6