24313-64-2Relevant articles and documents
Oxidation of aromatic anils by sodium perborate in aqueous acetic Acid Medium
Venkatesh,Karunakaran
, p. 739 - 744 (2014/06/09)
The kinetics of oxidation of 9 meta- and 15 para- substituted aromatic anils by sodium perborate were investigated in aqueous acetic acid medium. The reaction was second order with respect to aromatic anil and first order with respect to the sodium perborate. The increase of [H+] in this oxidation retards the rate of the reaction. The observed rate constant for the substituents were plotted against the Hammett constant, δ and a non-linear concave downward curve was obtained for the anils with substituents in the aniline moiety. The observed break in the log kobs versus δwas attributed to the transition state whereas the non-linear concave upward curve was observed for the substituents in the benzaldehyde moiety and a non-linear concave upward curve was observed for the substituents in the combination of aniline and benzaldehyde moiety. The electron withdrawing substituents fall on one side of the curve, having a negative ρvalue and the electron releasing substituents fall on the other side, with a positive ρvalue and a suitable mechanism was proposed.
Iron-catalyzed direct synthesis of imines from amines or alcohols and amines via aerobic oxidative reactions under air
Zhang, Erlei,Tian, Haiwen,Xu, Sendong,Yu, Xiaochun,Xu, Qing
supporting information, p. 2704 - 2707 (2013/07/19)
Abundant and cheap iron readily catalyzed the aerobic oxidative reactions of primary amines, secondary amines, benzylamines with anilines, and alcohols with amines by directly using air as the economic and safe oxidant, providing several direct, practical, and greener approaches for the preparation of useful imines.
Kinetic investigation of oxidation of aromatic anils by potassium peroxymonosulfate in aqueous acidic medium
Venkatesh,Karunakaran
, p. 542 - 550 (2013/07/26)
The kinetics of oxidation of aromatic anils to benzaldehyde and azobenzene by potassium peroxymonosulfate has been studied in aqueous acetic acid medium. The low dielectric constant of the medium facilitates the reactivity. It has been found that the variation in the ionic strength of the reaction has a negligible effect on the rate. Similarly, polymerization was not observed when acrylonitrile was added to the reaction mixture. This observation rules out the formation of any free radical in the reaction. The added Mn(II) increases the rate of the reaction, which indicates the involvement of two-electron transfer. Highly negative ΔS# values indicate a structured transition state. The deviation of the Hammett plot was noted, and a concave downward curve was obtained for the anils with substituents in the aniline moiety. The observed break in the log kobs versus σ is attributed to the transition state whereas the concave upward curve was observed for the substituents in the benzaldehyde moiety and in the combination of aniline and benzaldehyde moieties, and a suitable mechanism was proposed.
tert-Butyl isocyanide as a convertible reagent in Ugi reaction: Microwave-assisted preparation of 5,6-dihydropyrazolo[1,5-a]pyrazine-4,7-diones
Nikulnikov, Mikhail,Tsirulnikov, Sergey,Kysil, Volodymyr,Ivachtchenko, Alexandre,Krasavin, Mikhail
body text, p. 260 - 262 (2009/06/23)
tert-Butyl amides resulting from Ugi MCR of t-BuNC and 5-substituted- 1H-pyrazole-3-carboxylic acids with various aldehydes and amines undergo cyclization into 5,6-dihydropyrazolo[ 1,5-a]pyrazine-4,7-diones in glacial acetic acid under microwav
