244028-70-4Relevant articles and documents
Divergent solid-phase synthesis of natural product-inspired bipartite cyclodepsipeptides: Total synthesis of seragamide a
Arndt, Hans-Dieter,Rizzo, Stefano,N?cker, Christina,Wakchaure, Vijay N.,Milroy, Lech-Gustav,Bieker, Vanessa,Calderon, Abram,Tran, Tuyen T. N.,Brand, Silke,Dehmelt, Leif,Waldmann, Herbert
, p. 5311 - 5316 (2015)
Macrocyclic natural products (NPs) and analogues thereof often show high affinity, selectivity, and metabolic stability, and methods for the synthesis of NP-like macrocycle collections are of major current interest. We report an efficient solid-phase/cycl
Discovery of iodinated somatostatin analogues selective for hsst2 and hsst5 with excellent inhibition of growth hormone and prolactin release from rat pituitary cells
Moore, Sandra Blaj,Van Der Hoek, Joost,De Capua, Antonia,Van Koetsveld, Peter M.,Hofland, Leo J.,Lamberts, Steven W. J.,Goodman, Murray,Taulane, Joseph P.
, p. 6643 - 6652 (2007/10/03)
Inhibition of growth hormone (GH) and prolactin (PRL) release from the anterior pituitary gland is mediated through somatostatin receptor subtypes sst2 and sst5. It has been found that somatostatin (SS) analogues that are selective for both receptor subty
SOMATOSTATIN ANALOGS WITH INHIBITORY ACTIVITY TO GROWTH HORMONE RELEASE
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Page/Page column 24-25, (2008/06/13)
Provided are therapeutic and diagnostic somatostatin analogs including radiotherapeutic and radiodiagnostic reagents, and methods of making and use thereof.
Control of the iodination reaction on activated aromatic residues in peptides
Espuna, Gemma,Arsequell, Gemma,Valencia, Gregorio,Barluenga, Jose,Perez, Marta,Gonzalez, Jose M.
, p. 1307 - 1308 (2007/10/03)
By using a slight molar excess of the IPy2BF4 reagent in an acid containing medium, activated aromatic residues on Tyr derivatives and peptides selectively react yielding, as major products, the monoiododerivatives; this level of reaction control cannot be achieved by other iodinating methods.
