24417-01-4Relevant articles and documents
Ring-opening reactions of nonactivated aziridines catalyzed by tris(pentafluorophenyl)borane
Watson, Iain D. G.,Yudin, Andrei K.
, p. 5160 - 5167 (2007/10/03)
The ring-opening reactions of nonactivated aziridines with amine nucleophiles are efficiently catalyzed by tris(pentafluorophenyl)borane leading to derivatives of trans-1,2-diamines in high yields. A mechanistic investigation of the reaction suggests that in situ formed [(C6F5)3B(OH2)]· H2O catalyzes the opening through a Bronsted acid manifold.
Preparation of trans-1,2-diaminocyclohexane derivatives by lithium perchlorate catalyzed ring opening of aziridines
De Parrodi,Vazquez,Quintero,Juaristi
, p. 3295 - 3302 (2007/10/03)
N,N′-Dialkylated trans-1,2-diaminocyclohexane derivatives were synthesized with good overall yield via reaction of the corresponding N-alkylated cyclohexene aziridine with amines, in the presence of lithium perchlorate as catalyst.
