2444-19-1

Basic information

• Product Name: 4-HYDROXYPHENYL BENZOATE
• Synonyms: 1,4-Diphenol, 1-benzoate;4-HYDROXYPHENYL BENZOATE;P-HYDROXYPHENYL BENZOATE;Benzoic acid 4-hydroxyphenyl ester~Hydroquinone monobenzoate;Benzoic Acid 4-Hydroxyphenyl Ester;hydroquinone monobenzoate;1,4-Benzenediol 1-benzoate;p-Hydroquinone monobenzoate
• CAS NO: 2444-19-1
• Molecular Formula: C₁₃H₁₀O₃
• Molecular Weight: 214.22
• EINECS: 219-479-4
• Product Categories: Aromatic Esters
• Mol File: 2444-19-1.mol
• Article Data: 27

Chemical Properties

• Melting Point: 164-165°C
• Boiling Point: 376.6 °C at 760 mmHg
• Flash Point: 164.7 °C
• Appearance: /
• Density: 1.25 g/cm³
• Vapor Pressure: 3.3E-06mmHg at 25°C
• Refractive Index: 1.615
• Storage Temp.: 2-8°C
• PKA: 9.59±0.26(Predicted)
• BRN: 2050596
• CAS DataBase Reference: 4-HYDROXYPHENYL BENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXYPHENYL BENZOATE(2444-19-1)
• EPA Substance Registry System: 4-HYDROXYPHENYL BENZOATE(2444-19-1)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 2444-19-1(Hazardous Substances Data)

Usage

Uses

4-Hydroxyphenyl Benzoate is a useful intermediate and is used in the production of insecticide, Pyridalyl (P997113).

InChI:InChI=1/C13H10O3/c14-11-6-8-12(9-7-11)16-13(15)10-4-2-1-3-5-10/h1-9,14H

Upstream product

• 93-99-2 benzoic acid phenyl ester 
• 7732-18-5 water 
• 98-88-4 benzoyl chloride 
• 123-31-9 hydroquinone 
• 225529-40-8 4-benzoyloxy phenyl acetate 
• 6411-34-3 4-allyloxyphenol 
• 37592-20-4 1,4-bis(allyloxy)benzene 
• 88561-74-4 4-(allyloxy)phenyl benzoate 
• 65-85-0 benzoic acid 
• 100-52-7 benzaldehyde 
• 106-51-4 p-benzoquinone 
• 74206-92-1 carbonic acid benzyl ester-(4-hydroxy-phenyl ester) 
• 103-16-2 4-Benzyloxyphenol 
• 64-17-5 ethanol 

Downstream Products

• 109591-22-2 phosphoric acid diethyl ester-(4-benzoyloxy-phenyl ester) 
• 380153-99-1 4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)phenylbenzoate 
• 132239-98-6 2-Benzoyloxy-5-hydroxy-4'-cyano-azobenzene 
• 2621-51-4 4-<4-Benzoyloxy-phenoxy>-3.5-dinitro-benzoesaeure-aethylester 
• 2379-03-5 4-(4-Benzoyloxy-phenoxy)-3,5-dinitro-phenylessigsaeure-ethylester 
• 2379-05-7 N-acetyl-O'-benzoyl-3,5-dinitro-L-thyronine ethyl ester 
• 58069-02-6 2.6-dinitro-hydroquinone-4-benzoate 
• 762245-12-5 benzoic acid 4-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyloxy)-phenyl ester 
• 377048-36-7 benzoic acid 4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-decyloxy)-phenyl ester 
• 925424-66-4 benzoic acid 4-cyclohexyloxy-phenyl ester 
• 920283-15-4 4-[4-(4-Chlorbutyl)benzyloxy]phenyl-benzoat 
• 920283-24-5 2,2'-{4-[4-(4-Hydroxyphenoxymethyl)phenyl]butylimino}diethanol 
• 499789-97-8 4-(5-hydroxybenzoxazol-2-yl)benzonitrile 
• 149636-70-4 4-(5-hydroxybenzoxazol-2-yl)benzoic acid 

Relevant articles and documents

Metal-free approach for hindered amide-bond formation with hypervalent iodine(iii) reagents: application to hindered peptide synthesis

A new bio-inspired approach is reported for amide and peptide synthesis using α-amino esters that possess a potential activating group (PAG) at the ester residue. To activate the ester functionality under mild metal-free conditions, we exploited the facile dearomatization of phenols with hypervalent iodine(iii) reagents. Using a pyridine-hydrogen fluoride complex, highly reactive acyl fluoride intermediates can be successfully generated, thereby allowing for the smooth formation of sterically hindered amides and peptides from bulky amines and α-amino esters, respectively.

Nickel-catalyzed deallylation of aryl allyl ethers with hydrosilanes

An efficient and mild catalytic deallylation method of aryl allyl ethers is developed, with commercially available Ni(COD)2 as catalyst precursor, simple substituted bipyridine as ligand and air-stable hydrosilanes. The process is compatible with a variety of functional groups and the desired phenol products can be obtained with excellent yields and selectivity. Besides, by detection or isolation of key intermediates, mechanism studies confirm that the deallylation undergoes η3-allylnickel intermediate pathway.

An efficient and chemoselective deprotection of aryl tert-butyldimethylsilyl (TBDMS) ethers by NaCN

Phenolic tert-butyldimethylsilyl (TBDMS) ethers can be deprotected to yield phenols in excellent yield using sodium cyanide (NaCN) as catalyst in ethanol. The deprotectation of various phenolic TBDMS ethers were found to be very convenient, fast, high yielding and chemoselective.