24484-54-6

Basic information

• Product Name: 2-[3-(4-fluorophenyl)propyl]malonic acid
• Synonyms: 2-[3-(4-fluorophenyl)propyl]malonic acid
• CAS NO: 24484-54-6
• Molecular Weight: 240.231
• Mol File: 24484-54-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-[3-(4-fluorophenyl)propyl]malonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[3-(4-fluorophenyl)propyl]malonic acid(24484-54-6)
• EPA Substance Registry System: 2-[3-(4-fluorophenyl)propyl]malonic acid(24484-54-6)

Safety Data

• Hazardous Substances Data: 24484-54-6(Hazardous Substances Data)

Upstream product

• 459-32-5 (E)-4-fluorocinnamic acid 
• 702-15-8 3-(4-fluorophenyl)propan-1-ol 
• 141-82-2 malonic acid 
• 63416-70-6 3-(4-fluorophenyl)propanal 
• 459-57-4 4-fluorobenzaldehyde 
• 1462-12-0 diethyl ethylidenemalonate 

Downstream Products

• 24484-22-8 5-(4-fluorophenyl)-pentanoic acid 
• 1510820-22-0 N-(4-fluorophenyl)-5-(4-fluorophenyl)-2-(4-hydroxybenzyl)pentanamide 
• 204589-58-2 1-(4-fluorophenyl)-[3-(4-fluorophenyl)propyl]-4-(4-hydroxyphenyl)-2-azetidinone 
• 204589-92-4 5-(4-fluorophenyl)pentanoyl chloride 

Relevant articles and documents

Tandem IBX-Promoted Primary Alcohol Oxidation/Opening of Intermediate β,γ-Diolcarbonate Aldehydes to (E)-γ-Hydroxy-α,β-enals

A tandem IBX-promoted oxidation of primary alcohol to aldehyde and opening of intermediate β,γ-diolcarbonate aldehyde to (E)-γ-hydroxy-α,β-enal has been developed. Remarkably, the carbonate opening delivered exclusively (E)-olefin and no over-oxidation of γ-hydroxy was observed. The method developed has been extended to complete the stereoselective total synthesis of both (S)- and (R)-coriolides and d-xylo- and d-arabino-C-20 guggultetrols.