24715-90-0

Basic information

• Product Name: 4-PYRROLIDINOBUTYLAMINE
• Synonyms: 4-PyrrolidinbutylaMine;(4-pyrrolidin-1-ylbutyl)amine;4-1-pyrrolidinylbutan-1-amine;4-pyrrolidin-1-ylbutylamine;4-Pyrrolidin-1-yl-butylamine;1-Pyrrolidinebutanamine;TIMTEC-BB SBB010289;RARECHEM AL BW 0242
• CAS NO: 24715-90-0
• Molecular Formula: C₈H₁₈N₂
• Molecular Weight: 142.24
• Product Categories: Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines;pyrrole
• Mol File: 24715-90-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 97°C 15mm
• Flash Point: 79.4 °C
• Appearance: /
• Density: 0.923 g/cm³
• Vapor Pressure: 0.128mmHg at 25°C
• Refractive Index: 1.484
• Storage Temp.: 2-8°C(protect from light)
• PKA: 10.48±0.20(Predicted)
• Water Solubility: Soluble in water
• Sensitive: Air Sensitive
• CAS DataBase Reference: 4-PYRROLIDINOBUTYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PYRROLIDINOBUTYLAMINE(24715-90-0)
• EPA Substance Registry System: 4-PYRROLIDINOBUTYLAMINE(24715-90-0)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39
• RIDADR: 2735
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 24715-90-0(Hazardous Substances Data)

Usage

Uses

4-(1-Pyrrolidinyl)-1-butanamine is a useful reagent used in the preparation of imidazolidinedione derivatives used as antimalarial agents. A building block for organic synthesis.

Synthesis Reference(s)

Journal of the American Chemical Society, 95, p. 3038, 1973 DOI: 10.1021/ja00790a064

InChI:InChI=1/C8H18N2/c9-5-1-2-6-10-7-3-4-8-10/h1-9H2

Upstream product

• 123-75-1 pyrrolidine 
• 7664-41-7 ammonia 
• 109-99-9 tetrahydrofuran 
• 110-63-4 Butane-1,4-diol 

Downstream Products

• 1281969-45-6 5-[1-(4-cyanophenyl)-1H-pyrazol-5-yl]-6-methyl-2-oxo-N-(4-pyrrolidin-1-ylbutyl)-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide 
• 1224570-82-4 N-(4-pyrrolinobutyl)-N'-(3,4-dichlorophenyl)-guanidine 
• 1224570-67-5 N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-(4-pyrrolidin-1-yl-butyl)-guanidine 
• 1256271-03-0 (5R)-N₅-(4-bromophenyl)-(6R)-N₆-(4-pyrrolidin-1-yl-butyl)-(4S,7R)-[4,7-ethenylenespiro[2.4]heptane]-5,6-dicarboxamide 
• 869543-75-9 4-amino-3-(4-bromo-phenoxymethyl)-thieno[3,2-c]pyridine-7-carboxylic acid (4-pyrrolidin-1-yl-butyl)-amide 
• 505059-75-6 3-(4-chlorophenyl)-N'-((4-chlorophenyl)sulfonyl)-N-[4-(pyrrolidin-1-yl)butyl]-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamidine 
• 1197879-81-4 4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-N-(4-pyrrolidin-1-yl-butyl)-benzamide 
• 441295-44-9 4-[[[3-(1-pyrrolidinyl)propyl]amino]methyl]benzonitrile 
• 441295-48-3 4-[[[4-(1-pyrrolidinyl)butyl]amino]methyl]benzonitrile 
• 401817-09-2 N-{4-[2-(3-chlorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrimidin-2-yl}-N-(4-pyrrolidin-1-ylbutyl)amine 
• 252003-65-9 3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]amino]carbonyl]amino]-4-isothiazolecarboxamide 
• 252003-32-0 3-(2,5-difluoro-4-methyl-benzyloxy)-5-[3-(4-pyrrolidin-1-yl butyl)-ureido]-isothiazole-4-carboxylic acid amide 
• 64058-09-9 3-methyl-3-[4-(1-methyl-pyrrolidinium-1-yl)-butyl]-3-azonia-bicyclo[3.3.1]nonane; diiodide 

Relevant articles and documents

Steric effects in the catalytic amination of γ-, δ-, and ε-glycols

The amination of butane-1,4-diol, isomeric dipropylene glycols, and cyclohexane-1,4-diyldimethanol in the presence of nickel/copper/chromium catalysts has been studied. The effect of the initial glycol structure on the reaction selectivity has been estima