252049-03-9Relevant articles and documents
DNA functionalization by dynamic chemistry
Kanlidere, Zeynep,Jochim, Oleg,Cal, Marta,Diederichsen, Ulf
, p. 2136 - 2144 (2016)
Dynamic combinatorial chemistry (DCC) is an attractive method to efficiently generate libraries of molecules from simpler building blocks by reversible reactions under thermodynamic control. Here we focus on the chemical modification of DNA oligonucleotid
Synthesis of nucleoside analogues in a ball mill: Fast, chemoselective and high yielding acylation without undesirable solvents
Ravalico, Francesco,James, Stuart L.,Vyle, Joseph S.
supporting information; experimental part, p. 1778 - 1783 (2011/08/22)
The chemoselective acylation of primary aliphatic amines has been achieved in under ten minutes (and for aromatic amines under 120 min) using vibration ball-milling, avoiding undesirable solvents which are typically employed for such reactions (e.g. DMF).