25233-47-0

Basic information

• Product Name: M-ACETOACETANISIDIDE
• Synonyms: N-(3-METHOXYPHENYL)-3-OXOBUTANAMIDE;3-METHOXY-ACETOACETANILIDE;M-ACETOACETANISIDIDE;N-(3-Methoxyphenyl)-3-oxobutyramide;N-(3-Methoxyphenyl)acetoacetamide;Butanamide, N-(3-methoxyphenyl)-3-oxo-
• CAS NO: 25233-47-0
• Molecular Formula: C₁₁H₁₃NO₃
• Molecular Weight: 207.23
• Mol File: 25233-47-0.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 403.7°Cat760mmHg
• Flash Point: 198°C
• Appearance: /
• Density: 1.173g/cm³
• Vapor Pressure: 9.95E-07mmHg at 25°C
• Refractive Index: 1.552
• PKA: 11.19±0.46(Predicted)
• CAS DataBase Reference: M-ACETOACETANISIDIDE(CAS DataBase Reference)
• NIST Chemistry Reference: M-ACETOACETANISIDIDE(25233-47-0)
• EPA Substance Registry System: M-ACETOACETANISIDIDE(25233-47-0)

Safety Data

• Hazardous Substances Data: 25233-47-0(Hazardous Substances Data)

Usage

General Description

M-acetoacetanisidide is a chemical compound that belongs to the category of organic compounds known as beta-keto-esters. It is a yellow solid with a molecular formula of C12H15NO3 and a molecular weight of 221.3 g/mol. M-acetoacetanisidide is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. Its structure contains both ketone and ester functional groups, making it versatile for use in different chemical reactions. M-acetoacetanisidide is also used in the production of dyes and pigments, and as a reagent in organic synthesis. It is important to handle this compound with care as it may be harmful if it comes into contact with the skin or is ingested.

InChI:InChI=1/C11H13NO3/c1-8(13)6-11(14)12-9-4-3-5-10(7-9)15-2/h3-5,7H,6H2,1-2H3,(H,12,14)

Upstream product

• 536-90-3 m-Anisidine 
• 105-45-3 acetoacetic acid methyl ester 
• 141-97-9 ethyl acetoacetate 
• 5394-63-8 2,2,6-trimethyl-4H-1,3-dioxin-4-one 
• 674-82-8 4-methyleneoxetan-2-one 

Downstream Products

• 61304-90-3 N-phenyl-7-methoxy-4-methylquinolin-2(1H)-one 
• 167763-99-7 N-benzyl-7-methoxy-4-methylquinolin-2(1H)-one 
• 1565871-05-7 (E)-N-(3-methoxyphenyl)-2-oxo-4-phenyl-6-styryl-1,2,3,4-tetrahydropyrimidine-5-carboxamide 
• 1607003-02-0 3-acetyl-1-(3-methoxyphenyl)-1H-chromeno[4,3-b]pyridine-2,5-dione 
• 1588498-94-5 C₁₅H₁₉NO₃ 
• 1416792-51-2 C₁₃H₁₅NO₃ 
• 40053-37-0 4-methyl-7-methoxy-2(1H)-quinolinone 
• 223676-84-4 3-(4-aminobenzyl)-7-methoxy-4-methyl-2(1H)-quinolinone 

Relevant articles and documents

Ru-NHC-Catalyzed Asymmetric Hydrogenation of 2-Quinolones to Chiral 3,4-Dihydro-2-Quinolones

Direct enantioselective hydrogenation of unsaturated compounds to generate chiral three-dimensional motifs is one of the most straightforward and important approaches in synthetic chemistry. We realized the Ru(II)-NHC-catalyzed asymmetric hydrogenation of 2-quinolones under mild reaction conditions. Alkyl-, aryl- and halogen-substituted optically active dihydro-2-quinolones were obtained in high yields with moderate to excellent enantioselectivities. The reaction provides an efficient and atom-economic pathway to construct simple chiral 3,4-dihydro-2-quinolones. The desired products could be further reduced to tetrahydroquinolines and octahydroquinolones.

Nucleic acid binding dyes and uses therefor

The invention provides novel compounds and compositions of Formulas I and II, as well as methods of using them. The compounds can be used, for example, to quantify an amount of double stranded DNA in a sample subjected to nucleic acid amplification, or fo

Facile eco-friendly synthesis of novel chromeno[4,3-b]pyridine-2,5-diones and evaluation of their antimicrobial and antioxidant properties

Rapid and facileaccess to novel chromeno[4,3-b]pyridine-2,5-dione derivatives was achieved by a mild base catalysed reaction of 4-chloro-3-formylcoumarin and acetoacetamides in PEG-300 as recyclable solvent. The compounds were evaluated for their antimicrobial activities against 3 Gram-positive and 3 Gram-negative bacteria (Staphylococcus epidermis, Vibrio parahaemolyticus, Bacillus subtilis, Escherichia coli, Staphylococcus aureus and Klebsiella pneumonia) with Cefotaxime control. They were further subjected to antioxidant studies using DPPH test with ascorbic acid control. While compounds 5d and 5k showed promising broad spectrum antibacterial properties against all the evaluated bacteria, compound 5g exhibited good antioxidant properties. Indian Academy of Sciences.