25529-27-5Relevant articles and documents
Immobilized hydrogels for screening of molecular interactions
Dominguez, Melissa M.,Wathier, Michel,Grinstaff, Mark W.,Schaus, Scott E.
, p. 1064 - 1066 (2007)
Spatially arrayed, high-density microarrays enable the rapid assessment of biological recognition events, and this information is of widespread interest for those working in basic research laboratories as well as in the clinic. Today, one can find DNA, pr
DENTRITIC POLYMERS, CROSSLINKED GELS, AND THEIR USES IN ORTHOPEDIC APPLICATIONS
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Page/Page column 269-270, (2010/10/20)
The present invention provides compositions, kits, and methods for repairing cartilaginous tissue. Certain methods of the invention utilize dendritic macromolecules formed by treating a dendritic compound with light or a linking compound. In certain instances, the dendritic compounds have a lysine, cysteine, isocysteine residue or other nucleophilic group attached to their peripheries. Addition of a compound containing two or more electrophilic groups, such as aldehydes, activated esters, or acrylates, to the lysine-capped, cysteine-capped, or isocysteine-capped dendrimers produces a polymeric compound that can repair a cartilage defect.
Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions
Wathier, Michel,Jung, Pil J.,Carnahan, Michael A.,Kim, Terry,Grinstaff, Mark W.
, p. 12744 - 12745 (2007/10/03)
Dendritic macromers are attractive macromolecules for hydrogel formation since high cross-linking densities at low polymer concentration can be obtained, varied physical properties can be observed based on the macromer structure, and low viscous aqueous s
