25855-75-8

Basic information

• Product Name: Methanone, (2,6-dimethoxyphenyl)phenyl-
• CAS NO: 25855-75-8
• Molecular Formula: C15H14O3
• Molecular Weight: 242.274
• Mol File: 25855-75-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Methanone, (2,6-dimethoxyphenyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2,6-dimethoxyphenyl)phenyl-(25855-75-8)
• EPA Substance Registry System: Methanone, (2,6-dimethoxyphenyl)phenyl-(25855-75-8)

Safety Data

• Hazardous Substances Data: 25855-75-8(Hazardous Substances Data)

Upstream product

• 634-36-6 1,2,3-trimethoxybenzene 
• 98-88-4 benzoyl chloride 
• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 
• 23112-96-1 (2,6-dimethoxyphenyl)boronic acid 
• 1466-76-8 2-6-dimethoxybenzoic acid 
• 100-47-0 benzonitrile 
• 66185-72-6 7-(phenylcarbonyl)oxy-4-methyl-2H-1-benzopyran-2-one 
• 20312-83-8 8-Benzoyl-7-hydroxy-4-methylcoumarin 
• 3392-97-0 2,6-dimethoxybenzaldehyde 
• 591-51-5 phenyllithium 
• 151-10-0 1,3-Dimethoxybenzene 
• 127595-53-3 1-(2,6-dimethoxyphenyl)benzyl alcohol 
• 63411-81-4 benzoyl-resorcinol 

Downstream Products

• 124937-93-5 N-(3-(2,6-dimethoxyphenyl)-3-hydroxy-3phenylpropylidene)tert.butylamine 
• 1027522-54-8 (2-Benzoyl-3-hydroxy-phenoxy)-acetic acid methyl ester 
• 193738-65-7 4-Hydroxy-3-phenyl-benzofuran-2-carboxylic acid methyl ester 
• 63411-81-4 benzoyl-resorcinol 

Relevant articles and documents

Tetra- And Dinuclear Palladium Complexes Based on a Ligand of 2,8-Di-2-pyridinylanthyridine: Preparation, Characterization, and Catalytic Activity

Complexation of L [L = 5-phenyl-2,8-di-2-pyridinyl-anthyridine] with [Pd(CH3CN)4](BF4)2 and [Pd(CH3CN)3Cl](BF4) in a molar ratio of 1:2 rendered the corresponding dinuclear complexes [Pd2L (CH3CN)4](BF4)4 (1) and [Pd2L (CH3CN)2Cl2](BF4)2 (2), respectively. However, treatment of L with (COD)PdCl2 followed by anion exchange yielded a tetranuclear complex [Pd4L3Cl4](PF6)4(4a). Structures of these complexes are characterized by both spectroscopy and X-ray crystallography. Interconversion of these three complexes was studied via the manipulation of stoichiometric ratio of ligand to metal precursor. The catalytic activity of these complexes for carbonylative Suzuki-Miyaura cross-coupling was investigated. Complex 2 shows an excellent catalytic activity on the reaction of aryl iodide with arylboronic acid in the presence of atmospheric pressure of CO to give the corresponding benzophenones.

Hexafluoro-2-propanol-Promoted Intermolecular Friedel-Crafts Acylation Reaction

The intermolecular Friedel-Crafts acylation was carried out in hexafluoro-2-propanol to yield aryl and heteroaryl ketones at room temperature without any additional reagents.

An improved palladium(II)-catalyzed method for the synthesis of aryl ketones from aryl carboxylic acids and organonitriles

A palladium(II)-catalyzed decarboxylative protocol for the synthesis of aryl ketones has been developed. The addition of TFA was shown to improve the reaction yield and employing THF as solvent enabled the use of solid nitriles and in only a small excess. Using this method, five different benzoic acids reacted with a wide range of nitriles to produce 29 diverse (hetero)aryl ketone derivatives in up to 94% yield.