258839-82-6

Basic information

• Product Name: 7-(4-Nitrobenzyloxycarbonylamino)acetyl-imidazo[5,1-b]thiazole
• Synonyms: 7-(4-Nitrobenzyloxycarbonylamino)acetyl-imidazo[5,1-b]thiazole
• CAS NO: 258839-82-6
• Molecular Weight: 360.35
• Mol File: 258839-82-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-(4-Nitrobenzyloxycarbonylamino)acetyl-imidazo[5,1-b]thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(4-Nitrobenzyloxycarbonylamino)acetyl-imidazo[5,1-b]thiazole(258839-82-6)
• EPA Substance Registry System: 7-(4-Nitrobenzyloxycarbonylamino)acetyl-imidazo[5,1-b]thiazole(258839-82-6)

Safety Data

• Hazardous Substances Data: 258839-82-6(Hazardous Substances Data)

Upstream product

• 258839-09-7 7-azidoacetylimidazo[5,1-b]thiazole 
• 4457-32-3 4-nitrobenzyl chloroformate 
• 251-89-8 imidazo[5,1-b]thiazole 
• 258838-72-1 7-acetylimidazo[5,1-b]thiazole 

Downstream Products

• 258840-63-0 4-nitrobenzyl(1S,5R,6S)-6-((1R)-1-hydroxyethyl)-1-methyl-2-[7-(4-nitrobenzyloxy-carbonylamino)acetylimidazo[5,1-b]thiazol-2-yl]-1-carbapen-2-em-3-carboxylate 
• 258840-82-3 4-nitrobenzyl(5R,6S)-6-((1R)-1-hydroxyethyl)-2-[7-(4-nitrobenzyloxycarbonyl-amino)acetylimidazo[5,1-b]thiazol-2-yl]-1-carbapen-2-em-3-carboxylate 
• 258839-81-5 7-(4-nitrobenzyloxycarbonylamino)acetyl-2-(tri-n-butylstannyl)imidazo[5,1-b]thiazole 

Relevant articles and documents

Carbapenem derivatives

Disclosed is a novel carbapenem derivative having a substituted imidazo[5,1-b]thiazole group at the 2-position on the carbapenem ring have high anti-microbial activities against β-lactamase producing bacteria, MRSA, resistant-Pseudomonas aeruginosa, PRSP, enterococci, and influenza, and high stabilities to DHP-1. According to the present invention, there is provided a compound represented by the formula (I), or a pharmacologically acceptable salt thereof or an ester at the 3-position on the carbapenem ring thereof: