259542-75-1

Basic information

• Product Name: N-{[4-phenyl-5-oxo-2-hydroisoxazol-2-yl]methyl}acetamide
• Synonyms: N-{[4-phenyl-5-oxo-2-hydroisoxazol-2-yl]methyl}acetamide
• CAS NO: 259542-75-1
• Molecular Weight: 232.239
• Mol File: 259542-75-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-{[4-phenyl-5-oxo-2-hydroisoxazol-2-yl]methyl}acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{[4-phenyl-5-oxo-2-hydroisoxazol-2-yl]methyl}acetamide(259542-75-1)
• EPA Substance Registry System: N-{[4-phenyl-5-oxo-2-hydroisoxazol-2-yl]methyl}acetamide(259542-75-1)

Safety Data

• Hazardous Substances Data: 259542-75-1(Hazardous Substances Data)

Upstream product

• 17838-69-6 ethyl 3-oxo-2-phenylpropanoate 
• 101-97-3 Ethyl 2-phenylethanoate 
• 17147-69-2 4-phenylisoxazol-5(2H)-one 
• 13831-32-8 N-(hydroxymethyl)acetamide acetate (ester) 

Downstream Products

• 259542-35-3 N-{[4-(4-acetylphenyl)-5-oxo-2-hydroisoxazol-2-yl]methyl}acetamide 

Relevant articles and documents

Discovery of isoxazolinone antibacterial agents. Nitrogen as a replacement for the stereogenic center found in oxazolidinone antibacterials

A series of potential antimicrobial derivatives possessing bioisosteric replacements for the central oxazolidinone ring found in oxazolidinone antibacterials have been prepared. The design concept involved replacement of the requisite sp3-hybridized stereogenic center found at the 5-position of the oxazolidinone with a nitrogen atom. The synthesis and antibacterial activity of three such ring systems, the benzisoxazolinones, pyrroles, and isoxazolinones is described.