26046-90-2

Basic information

• Product Name: 3-(Methylseleno)-L-alanine
• Synonyms: SE-METHYLSELENO-L-CYSTEINE;SEMC;(R)-2-AMINO-3-(METHYLSELENO)PROPIONIC ACID;SE-METHYLSELENO-L-CYSTEINE 98%;L-Se-Methylselenocysteine;(2R)-2-amino-3-methylselanyl-propanoic acid;SELENIUMMETHYLSELENOCYSTEINE;(R)-2-Amino-3-methylselanyl propionic acid
• CAS NO: 26046-90-2
• Molecular Formula: C₄H₉NO₂Se
• Molecular Weight: 182.08
• Product Categories: Antioxidant and Free Radical ScavengersApoptosis and Cell Cycle;Cell Cycle;Cell Cycle Regulators;AntioxidantCancer Research;Biochemicals Found in Plants;Chemopreventive Agents;Nutrition Research;food additives
• Mol File: 26046-90-2.mol

Chemical Properties

• Melting Point: 177 °C(dec.)
• Boiling Point: 327.976 °C at 760 mmHg
• Flash Point: 152.155 °C
• Appearance: White to slightly yellow/Powder
• Vapor Pressure: 0mmHg at 25°C
• Storage Temp.: −20°C
• PKA: 2.17±0.10(Predicted)
• CAS DataBase Reference: 3-(Methylseleno)-L-alanine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Methylseleno)-L-alanine(26046-90-2)
• EPA Substance Registry System: 3-(Methylseleno)-L-alanine(26046-90-2)

Safety Data

• Hazard Codes: T,N
• Statements: 23/25-33-50/53
• Safety Statements: 20/21-28-45-60-61-28A
• RIDADR: UN 3283 6.1/PG 2
• WGK Germany: 3
• F: 10-23
• Hazardous Substances Data: 26046-90-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-(Methylseleno)-L-alanine is used as an inhibitor for [application type] DMBA-induced mammary tumors [application reason] due to its potential anti-cancer properties. It plays a significant role in the development of treatments and therapies for breast cancer, showcasing its importance in the pharmaceutical sector.
Used in Nutritional Supplements:
Given its status as a selenium-containing amino acid, 3-(Methylseleno)-L-alanine is used as a nutritional supplement [application type] for enhancing the selenium content in the human diet [application reason]. Selenium is an essential trace element that plays a crucial role in various physiological functions, including antioxidant defense and immune system support.
Used in Agricultural Industry:
In the agricultural industry, 3-(Methylseleno)-L-alanine can be used as a feed additive [application type] to improve the selenium content in livestock [application reason]. This can lead to enhanced animal health and productivity, as well as increased selenium levels in animal-derived food products, which can contribute to better human health.
Used in Cosmetics:
3-(Methylseleno)-L-alanine may also find applications in the cosmetics industry [application industry] as an active ingredient [application type] for its potential antioxidant and anti-aging properties [application reason]. Its incorporation into skincare products could provide consumers with the benefits of selenium for maintaining healthy skin.

InChI:InChI=1/C4H9NO2SSe/c1-9-5-3(2-8)4(6)7/h3,5,8H,2H2,1H3,(H,6,7)

Downstream Products

• 127-17-3 2-oxo-propionic acid 
• 2574-71-2 3-methylseleno-2-amino-propionic acid 
• 1403762-63-9 (R)-N-(2-(1H-indol-3-yl)ethyl)-1-((3-(methylselanyl)-1-oxo-1-(phenethylamino)propan-2-yl)amino)cyclohexanecarboxamide 

Relevant articles and documents

Synthetic method for Se-methylselenocysteine

The invention discloses a synthetic method for Se-methylselenocysteine, and belongs to the field of fine chemical or organic synthesis. The method comprises the following steps: performing a catalyticreaction by using 2-methyl-4-benzylidene-5-oxazolidinone (I) shown in the description and dimethyldiselenide (II) shown in the description as raw materials to obtain a compound (III), performing catalytic hydrogenation to obtain a compound (IV), finally performing hydrolysis, and adjusting a pH to obtain the target compound (V) shown in the description. The method disclosed by the invention has the advantages that the raw materials are cheap and easy to obtain, the preparation process conditions are mild and controllable, the reaction temperature and time are moderate, the utilization rate ofthe raw materials is higher, and the total yield is high, wherein the total yield reaches 65% or more.

Manufacturing processes for Se-methyl-L-selenocysteine

Convenient processes are described for the synthesis of L-Se-methyselenocysteine from chloroalanine derivatives. The process is easily extendable to other selenium substituted amino acids. DL-Se-methyselenocysteine is easily obtained by a benzaldehyde-catalyzed racemization of L-Se-methyselenocysteine.