2610-95-9

Basic information

• Product Name: 6,6-Dimethyltetrahydro-2H-pyran-2-one
• Synonyms: 5-Methyl-5-hydroxyhexanoic acid lactone;6,6-Dimethyltetrahydro-2H-pyran-2-one;Tetrahydro-6,6-dimethyl-2H-pyran-2-one
• CAS NO: 2610-95-9
• Molecular Formula: C₇H₁₂O₂
• Molecular Weight: 128.17
• Mol File: 2610-95-9.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 206.3°C at 760 mmHg
• Flash Point: 74.8°C
• Appearance: /
• Density: 0.967g/cm³
• Vapor Pressure: 0.239mmHg at 25°C
• Refractive Index: 1.428
• CAS DataBase Reference: 6,6-Dimethyltetrahydro-2H-pyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6,6-Dimethyltetrahydro-2H-pyran-2-one(2610-95-9)
• EPA Substance Registry System: 6,6-Dimethyltetrahydro-2H-pyran-2-one(2610-95-9)

Safety Data

• Hazardous Substances Data: 2610-95-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H12O2/c1-7(2)5-3-4-6(8)9-7/h3-5H2,1-2H3

Upstream product

• 1003-17-4 2,2-dimethyltetrahydrofuran 
• 628-46-6 5-methylhexanoic acid 
• 5636-65-7 5-methyl-4-hexenoic acid 
• 802294-64-0 propionic acid 
• 115-11-7 isobutene 
• 503-66-2 3-hydroxypropionic acid 
• 77437-98-0 2-methylhept-6-en-2-ol 
• 13984-57-1 ethyl 5-oxohexanoate 
• 18006-13-8 methyltriisopropoxytitanium(IV) 
• 3121-82-2 2,2-dimethylpentane-1,5-diol 
• 616-87-5 isoamylmalonic acid 
• 22539-81-7 dimethyl 2-(3-methylbut-2-enyl)malonic acid 
• 75-16-1 methylmagnesium bromide 
• 1462-11-9 1,1-dimethyl-1,5-pentanediol 

Downstream Products

• 85559-25-7 6,6-Dimethyl-3-phenylselanyl-tetrahydro-pyran-2-one 
• 85570-69-0 6,6-Dimethyl-3,3-bis-phenylselanyl-tetrahydro-pyran-2-one 
• 26909-60-4 dimethyl 2-hydroxy-2-(3-hydroxy-3-methylbutyl)succinate 
• 82027-10-9 2'-(phenylseleno)dihydrocatalpalactone 
• 1585-68-8 catalpalactone 
• 122993-77-5 5,6-Dihydro-6,6-dimethyl-3-(4-methylphenylhydrazono)pyran-2(4H)-one 
• 110977-82-7 5,6-Dihydro-6,6-dimethyl-3-(phenylhydrazono)pyran-2(4H)-one 

Relevant articles and documents

Aromatic ring synthesis by 1,3-Michael-Claisen annulation: Application to a Trolox analogue and to Precocene II

A Trolox analogue, 3,4-dihydro-2-ethoxycarbonyl-6-methoxy-7-hydroxybenzopyran and Precocene II, were prepared from substituted α-methylene-δ-valerolactone and 1,1-bis-(methylthio)-2-propanone or butanone, via a 1,3-Michael-Claisen annulation.

Synthesis of the ester side chains of homoharringtonine and harringtonine using lactones as building blocks

The efficient synthesis of the ester side chains of homoharringtonine and harringtonine using lactones as building blocks has been developed. The synthesis used classic reactions from readily available starting materials. Reactions of the lactone bearing

Calcium(II)- And Triflimide-Catalyzed Intramolecular Hydroacyloxylation of Unactivated Alkenes in Hexafluoroisopropanol

We report an efficient intramolecular hydroacyloxylation of unactivated alkenes, offering a streamlined access to relevant γ-lactones, which features the utilization of either a calcium(II) salt or triflimide as a catalyst in hexafluoroisopropanol. This method could be applied to the synthesis of natural products and the late-stage functionalization of natural and bioactive molecules. Additionally, DFT computations were used to elucidate the twist of reactivity observed between the hydroamidation and hydroacyloxylation of unactivated alkenes regarding the formation of 5- and 6-membered rings.

Formation of δ-Lactones with anti-Baeyer–Villiger Regiochemistry: Investigations into the Mechanism of the Cerium-Catalyzed Aerobic Coupling of β-Oxoesters with Enol Acetates

The cerium-catalyzed, aerobic coupling of β-oxoesters with enol acetates and dioxygen yields δ-lactones with a 1,4-diketone moiety. In contrast to the Baeyer–Villiger oxidation (BVO), where the higher substituted residue migrates; in the case of this oxid