261638-97-5

Basic information

• Product Name: 2-(3,3-diMethylbut-1-en-2-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane
• Synonyms: 2-(3,3-diMethylbut-1-en-2-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane;2-(3,3-Dimethyl-1-buten-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-(2,2-Dimethyl-1-methylen-propyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane;2-(3,3-DIMETHYLBUT-1-EN-2-YL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE(WXC07809)
• CAS NO: 261638-97-5
• Molecular Formula: C12H23BO2
• Molecular Weight: 210.12082
• Mol File: 261638-97-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 213.0±23.0 °C(Predicted)
• Appearance: /
• Density: 0.87±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2-(3,3-diMethylbut-1-en-2-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,3-diMethylbut-1-en-2-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane(261638-97-5)
• EPA Substance Registry System: 2-(3,3-diMethylbut-1-en-2-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane(261638-97-5)

Safety Data

• Hazardous Substances Data: 261638-97-5(Hazardous Substances Data)

Usage

Type of compound

Boron-containing compound

Usage

Commonly used in organic synthesis reactions, particularly in the formation of carbon-carbon and carbon-heteroatom bonds

Reactivity

Highly reactive and can undergo various chemical reactions, such as cross-coupling reactions and alkylations

Value

Valuable reagent in the field of organic chemistry, used in the synthesis of pharmaceuticals, agrochemicals, and materials science

Stability

Known for its high stability, making it a popular choice in the development of new chemical reactions and processes.

Upstream product

• 917-92-0 3,3-Dimethylbut-1-yne 
• 7732-18-5 water 
• 73183-34-3 bis(pinacol)diborane 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 29443-60-5 3,3-dimethyl-2-iodo-1-butene 
• 27701-32-2 3,3-dimethyl-1-butenyl-2-triflate 
• 33693-77-5 2-Bromo-3,3-dimethyl-1-butene 

Downstream Products

• 1142225-73-7 methyl 3-(1-(1,1-dimethylethyl)ethenyl)-4-(((trifluoromethyl)sulfonyl)oxy)benzoate 
• 1142225-71-5 methyl 3-(1-(1,1-dimethylethyl)ethenyl)-4-hydroxybenzoate 

Relevant articles and documents

Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway

Reported is the identification of the furo[3,2-b]pyridine core as a novel scaffold for potent and highly selective inhibitors of cdc-like kinases (CLKs) and efficient modulators of the Hedgehog signaling pathway. Initially, a diverse target compound set was prepared by synthetic sequences based on chemoselective metal-mediated couplings, including assembly of the furo[3,2-b]pyridine scaffold by copper-mediated oxidative cyclization. Optimization of the subseries containing 3,5-disubstituted furo[3,2-b]pyridines afforded potent, cell-active, and highly selective inhibitors of CLKs. Profiling of the kinase-inactive subset of 3,5,7-trisubstituted furo[3,2-b]pyridines revealed sub-micromolar modulators of the Hedgehog pathway.

Iridium-catalyzed enantioselective hydrogenation of alkenylboronic esters

Choose the right ligand: An iridium complex derived from a phosphino-imidazoline ligand is a highly efficient catalyst for the asymmetric hydrogenation of terminal vinyl boronic esters (see scheme). On the other hand, trisubstituted alkenyl-boronates can

CONFORMATIONALLY CONSTRAINED CARBOXYLIC ACID DERIVATIVES USEFUL FOR TREATING METABOLIC DISORDERS

The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I or the general formula III: where the definitions of the variables are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.