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N-HYDROXY-2-PYRIDIN-3-YL-ACETAMIDINE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 261735-05-1 Structure
  • Basic information

    1. Product Name: N-HYDROXY-2-PYRIDIN-3-YL-ACETAMIDINE
    2. Synonyms: N-HYDROXY-2-PYRIDIN-3-YL-ACETAMIDINE
    3. CAS NO:261735-05-1
    4. Molecular Formula: C7H9N3O
    5. Molecular Weight: 151.16586
    6. EINECS: N/A
    7. Product Categories: pharmacetical
    8. Mol File: 261735-05-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-HYDROXY-2-PYRIDIN-3-YL-ACETAMIDINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-HYDROXY-2-PYRIDIN-3-YL-ACETAMIDINE(261735-05-1)
    11. EPA Substance Registry System: N-HYDROXY-2-PYRIDIN-3-YL-ACETAMIDINE(261735-05-1)
  • Safety Data

    1. Hazard Codes: T
    2. Statements: 25
    3. Safety Statements: 45
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 261735-05-1(Hazardous Substances Data)

261735-05-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 261735-05-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,1,7,3 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 261735-05:
(8*2)+(7*6)+(6*1)+(5*7)+(4*3)+(3*5)+(2*0)+(1*5)=131
131 % 10 = 1
So 261735-05-1 is a valid CAS Registry Number.

261735-05-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name N'-hydroxy-2-pyridin-3-ylethanimidamide

1.2 Other means of identification

Product number -
Other names (Z)-3-Pyridylacetamidoxim

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:261735-05-1 SDS

261735-05-1Upstream product

261735-05-1Relevant articles and documents

Potent and selective nonpeptidic inhibitors of procollagen C-proteinase

Fish, Paul V.,Allan, Gillian A.,Bailey, Simon,Blagg, Julian,Butt, Richard,Collis, Michael G.,Greiling, Doris,James, Kim,Kendall, Jackie,McElroy, Andrew,McCleverty, Dawn,Reed, Charlotte,Webster, Robert,Whitlock, Gavin A.

, p. 3442 - 3456 (2008/02/11)

6-Cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-yl)hexanamides were previously disclosed as inhibitors of procollagen C-proteinase (PCP) culminating in the identification of amide 1. Our objective was to discover a second inhibitor that would have improved affinity for PCP and to optimize properties for transepidermal delivery (TED) to intact skin. Further investigation of this template identified a number of potent PCP inhibitors (IC50 values of 2-6 nM) with improved TED flux. Sulfonamide 56 had excellent PCP enzyme activity when measured with a peptide substrate (Ki 8.7 nM) or with the endogenous substrate procollagen (IC50 3.4 nM) and demonstrates excellent selectivity over MMPs involved in wound healing (>10 000-fold). In the fibroplasia model, 56 inhibited deposition of insoluble collagen by 76 ± 2% at 10 μM and was very effective at penetrating human skin in vitro with a TED flux of 1.5 μg/cm2/h, which compares favorably with values for agents that are known to penetrate skin well in vivo. Based on this profile, 56 (UK-421,045) was selected as a candidate for further preclinical evaluation as a topically applied, dermal anti-scarring agent.

CCR5 ANTAGONISTS AS THERAPEUTIC AGENTS

-

Page 209, (2010/02/07)

The present invention relates to compounds of formula (I) or pharmaceutically acceptable derivatives thereof, useful in the treatment or prophylaxis of CCR5-related diseases and disorders, for example, in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).

Aryl and heteroaryl alkoxynaphthalene derivatives

-

, (2008/06/13)

Compounds of the formula wherein R1, R2, R4, R23, R24, R25 and R26 are defined as in the specification. These compounds are useful psychotherapeutics and are potent serotonin (5-HT1) agonists and antagonists.

Synthesis of 4,5-dihydro 1,2,4-oxadiazoles from N-unsubstituted amidoximes

Lessel,Herfs

, p. 22 - 26 (2007/10/03)

4,5-Dihydro 1,2,4-oxadiazoles can be synthesized from aromatic and araliphatic amidoximes by cyclocondensation with aldehydes and ketones. Resulting heterocycles differ in substitution at C-3 and C-5 showing the scope of the simple reaction.

Use of naphthalene derivatives in treating lung carcinoma

-

, (2008/06/13)

A method of inhibiting cell growth in human small cell lung carcinoma comprising administering to a mammal in need of such treatment a cell growth inhibitory amount of a compound of the formula STR1

Use of naphthalene derivatives in treating lung carcinoma

-

, (2008/06/13)

The use of a compound of the formula or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for inhibiting cell growth in human small cell lung carcinoma through inhibition of the 5HT1D receptor.

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