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26241-63-4

4ALPHA-PHORBOL, also known as phorbol 4-alpha-acetate, is a highly toxic and irritant compound derived from certain plants, particularly those in the Euphorbiaceae family. It is recognized for its potent tumor-promoting properties and its association with skin cancer development. As a strong activator of protein kinase C, 4ALPHA-PHORBOL significantly influences intracellular signaling and gene expression, making it a valuable tool in scientific research for investigating cellular processes, especially those related to cancer.

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  • 5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one,1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-,(1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-

    Cas No: 26241-63-4

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  • Hangzhou J&H Chemical Co., Ltd.
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  • 5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one,1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-,(1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)- 26241-63-4

    Cas No: 26241-63-4

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  • Shanghai Upbio Tech Co.,Ltd（expird）
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  • 26241-63-4 Structure

  • Basic information

    1. Product Name: 4ALPHA-PHORBOL
    2. Synonyms: 4ALPHA,9ALPHA,12BETA,13ALPHA,20-PENTAHYDROXYTIGILIA-1,6-DIEN-3-ONE;4ALPHA,9ALPHA,12BETA,13ALPHA,20-PENTAHYDROXYTIGLIA-1,6-DIEN-3-ONE;4ALPHA-PHORBOL;4-ALPHA-PHR;ISOPHORBOL;4A-phorbol;A-PHORBOL);4A-PHORBOL, 99+%
    3. CAS NO:26241-63-4
    4. Molecular Formula: C20H28O6
    5. Molecular Weight: 364.43
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 26241-63-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 572°C at 760 mmHg
    3. Flash Point: 313.8°C
    4. Appearance: white/powder
    5. Density: 1.415g/cm3
    6. Vapor Pressure: 1.83E-15mmHg at 25°C
    7. Refractive Index: 1.648
    8. Storage Temp.: −20°C
    9. Solubility: N/A
    10. CAS DataBase Reference: 4ALPHA-PHORBOL(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4ALPHA-PHORBOL(26241-63-4)
    12. EPA Substance Registry System: 4ALPHA-PHORBOL(26241-63-4)

  • Safety Data

    1. Hazard Codes: T+
    2. Statements: 26/27/28-36/37/38
    3. Safety Statements: 26-27-36/37/39-45
    4. RIDADR: UN 2811 6.1/PG 3
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: 6.1(b)
    8. PackingGroup: III
    9. Hazardous Substances Data: 26241-63-4(Hazardous Substances Data)

26241-63-4 Usage

Uses

Used in Scientific Research:
4ALPHA-PHORBOL is used as a research tool for studying cellular processes, specifically those involved in the development and progression of cancer. Its potent effects on protein kinase C activation allow researchers to explore the intricate mechanisms of cell signaling and gene regulation in the context of tumorigenesis.
Due to its highly toxic and irritant nature, 4ALPHA-PHORBOL is not suitable for clinical or therapeutic applications. Its use is strictly limited to controlled laboratory settings where its potential to induce cancer can be mitigated and its scientific value can be harnessed for advancing our understanding of cancer biology.

Check Digit Verification of cas no

The CAS Registry Mumber 26241-63-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,2,4 and 1 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 26241-63:
(7*2)+(6*6)+(5*2)+(4*4)+(3*1)+(2*6)+(1*3)=94
94 % 10 = 4
So 26241-63-4 is a valid CAS Registry Number.
InChI:InChI=1/C20H28O6/c1-9-5-13-18(24,15(9)22)7-11(8-21)6-12-14-17(3,4)20(14,26)16(23)10(2)19(12,13)25/h5-6,10,12-14,16,21,23-26H,7-8H2,1-4H3/t10-,12+,13-,14-,16-,18+,19-,20-/m1/s1

26241-63-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Isophorbol

1.2 Other means of identification

Product number -
Other names 4-ALPHA-PHORBOL

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:26241-63-4 SDS

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