26278-70-6

Basic information

• Product Name: 3-methoxy-3-phenyl-propionaldehyde dimethylacetal
• Synonyms: 3-methoxy-3-phenyl-propionaldehyde dimethylacetal
• CAS NO: 26278-70-6
• Molecular Weight: 210.273
• Mol File: 26278-70-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methoxy-3-phenyl-propionaldehyde dimethylacetal(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methoxy-3-phenyl-propionaldehyde dimethylacetal(26278-70-6)
• EPA Substance Registry System: 3-methoxy-3-phenyl-propionaldehyde dimethylacetal(26278-70-6)

Safety Data

• Hazardous Substances Data: 26278-70-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 26269-57-8 trans-1-methoxy-2-phenylcyclopropane 
• 107-25-5 methoxyethene 
• 1125-88-8 benzaldehyde dimethyl acetal 

Downstream Products

• 30076-98-3 (3,3-dimethoxypropyl)benzene 

Relevant articles and documents

Relative Reactivities of Acetals and Orthoesters in Lewis Acid Catalyzed Reactions with Vinyl Ethers. A Systematic Investigation of the Synthetic Potential of Acetals and Orthoesters in Electrophilic Alkoxyalkylations of Enol Ethers

The relative reactivities of acetals and orthoesters in BF3OEt2-catalyzed reactions with methyl vinyl ether (-78 deg C, CH2Cl2) have been determined by competition experiments.A reactivity increase by 5 orders of magnitude was found in the series: saturated acetals rel values of the para-substituted benzaldehyde acetals follow a Hammett ? correlation (ρ = -4.6).Whereas the krel values of the aldehyde acetals are correlated with the corresponding rate constants of acid-catalyzed hydrolyses, ketals and orthoesters devaite from this correlation.It is concluded that the krel listing in Scheme II can be used to predict the results of Lewis acid catalyzed additions of acetals and orthoesters toward vinyl ethers: The formation of 1:1 addition products may only be expected, if the relevant functional group of the reactants is listed below the functional group of the potential 1:1 products.