2637-76-5

Basic information

• Product Name: 1-ACETYLPIPERIDINE-3-CARBOXYLIC ACID
• Synonyms: 1-ACETYLPIPERIDINE-3-CARBOXYLIC ACID;3-piperidinecarboxylic acid, 1-acetyl-;1-ACETYL-3-PIPERIDINECARBOXYLIC ACID;1-acetyl-3-piperidinecarboxylic acid(SALTDATA: FREE);N-Acetylnipecotic acid;1-acetylnipecotic acid;1-ethanoylpiperidine-3-carboxylic acid;N-Ac-RS-3-Piperidinecarboxylic acid
• CAS NO: 2637-76-5
• Molecular Formula: C₈H₁₃NO₃
• Molecular Weight: 171.19
• Mol File: 2637-76-5.mol

Chemical Properties

• Melting Point: 131-132℃
• Boiling Point: 374.039°C at 760 mmHg
• Flash Point: 180.013°C
• Appearance: /
• Density: 1.213
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.507
• PKA: 4.25±0.20(Predicted)
• CAS DataBase Reference: 1-ACETYLPIPERIDINE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ACETYLPIPERIDINE-3-CARBOXYLIC ACID(2637-76-5)
• EPA Substance Registry System: 1-ACETYLPIPERIDINE-3-CARBOXYLIC ACID(2637-76-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 2637-76-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-Acetylpiperidine-3-carboxylic acid is used as a key intermediate for the synthesis of various drugs and bioactive compounds, contributing to the development of new therapeutic agents.
Used in Research and Development:
1-Acetylpiperidine-3-carboxylic acid is utilized in research and development for the exploration of its potential applications and the creation of new molecules with therapeutic properties, expanding the scope of its use in the pharmaceutical field.

InChI:InChI=1/C8H13NO3/c1-6(10)9-4-2-3-7(5-9)8(11)12/h7H,2-5H2,1H3,(H,11,12)

Upstream product

• 498-95-3 nipecotic acid 

Downstream Products

• 781664-53-7 1-acetyl-piperidine-3-carbonyl chloride 
• 712270-09-2 (3S)-1-acetyl-N-(2'-anilino-4,4'-bipyridin-2-yl)piperidine-3-carboxamide 
• 881920-19-0 1-(3-(4-bromophenyl)piperidin-1-yl)ethan-1-one 

Relevant articles and documents

Tricyclic compounds

Novel compounds of Formula STR1 are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of the formula to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.

Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases

A method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells is disclosed. The method comprises the administration of a compound of Formula 1.0: STR1 to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being. Novel compounds of formulas 5.0, 5.1 and 5.2, wherein R is --C(R20)(R21)(R46), and 5.3, 5.3A and 5.3B, wherein R is --N(R25)(R48), are disclosed. Also disclosed are processes for making 3-substituted compounds of Formulas 5.0, 5.1, 5.2 and 5.3. Further disclosed are novel compounds which are intermediates in the process for making 3-substituted compounds of Formulas 5.0, 5.1, 5.2 and 5.3.

Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases

Novel compounds of Formula (7.0a), (7.0b) or (7.0c): STR1 are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of the formula (7.0a), (7.0b) or (7.0c) to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.