2643-85-8

Basic information

• Product Name: OXYPEUCEDANINHYDRATE
• Synonyms: (+)-4-[(R)-2,3-Dihydroxy-3-methylbutoxy]-7H-furo[3,2-g][1]benzopyran-7-one;Hydroxypeucedanin hydrate;Prangol;Prangolarin hydrate;Aviprin;Oxypeucedanin hydrate, 98%, from Peucedanum praeruptorum Dunn
• CAS NO: 2643-85-8
• Molecular Formula: C₁₆H₁₆O₆
• Molecular Weight: 304.29
• Product Categories: Coumarins
• Mol File: 2643-85-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 187-188℃
• Boiling Point: 544.3°C at 760 mmHg
• Flash Point: 283°C
• Appearance: /
• Density: 1.386±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 1.12E-12mmHg at 25°C
• Refractive Index: 1.63
• PKA: 13.80±0.20(Predicted)
• CAS DataBase Reference: OXYPEUCEDANINHYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: OXYPEUCEDANINHYDRATE(2643-85-8)
• EPA Substance Registry System: OXYPEUCEDANINHYDRATE(2643-85-8)

Safety Data

• Hazardous Substances Data: 2643-85-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H16O6/c1-16(2,19)13(17)8-21-15-9-3-4-14(18)22-12(9)7-11-10(15)5-6-20-11/h3-7,13,17,19H,8H2,1-2H3

Upstream product

• 870-63-3 prenyl bromide 
• 484-20-8 bergapten 
• 486-60-2 bergaptol 
• 482-45-1 isoimperatorin 
• 737-52-0 oxypeucedanin 

Downstream Products

• 362467-97-8 1,3,4,5-tetraacetoxy-cyclohexanecarboxylic acid 2-hydroxy-2-methyl-1-(7-oxo-7H-furo[3,2-g]chromen-4-yloxymethyl)-propyl ester 

Relevant articles and documents

Benzofuran and coumarin derivatives from the root of Angelica dahurica and their PPAR-γ ligand-binding activity

A phytochemical investigation of the root of Angelica dahurica led to the isolation of benzofuran and coumarin derivatives. This is the first report of the isolation and identification of three furanocoumarin sulfates from A. dahurica root. The structures of a total of twelve undescribed compounds were determined by extensive spectroscopic analysis, including 2D NMR data, hydrolysis, and solvolysis, followed by either physicochemical and spectroscopic data or X-ray crystallographic analysis. The isolated compounds were evaluated for their PPAR-γ ligand-binding activity, and six compounds showed significant PPAR-γ ligand-binding activity. In particular, the undescribed benzofuran derivative, 3-[6,7-furano-9-hydroxy-4-(2″,3″-dihydroxy-3″-methylbutyloxy)]-phenyl propionic acid, exhibited the most potent PPAR-γ ligand-binding activity and accumulated intracellular lipid in 3T3-L1 cells.

Design, synthesis and evaluation of furanocoumarin monomers as inhibitors of CYP3A4

A number of furanocoumarins isolated from grapefruit juice have been found to inhibit CYP3A4 activity in vitro. In this study, we have designed and synthesised a range of analogues based on bergamottin to investigate the relationship between chemical stru

STEROIDS, CHROMONE AND COUMARINS FROM ANGELICA OFFICINALIS

From the ethyl acetate extract of the fresh roots of Angelica officinalis var. himaliaca, besides sitosterol, pregnenolone, peucenin-7-methyl ether, osthol and 18 furanocoumarins have been characterized by spectroscopic methods, including 13C NMR, and some chemical transformations. - Keywords: Angelica officinalis; Umbelliferae; root; pregnenolone; sitosterol; osthol; peucenin-7-methyl ether; furanocoumarins.