26763-19-9 Usage
Uses
Used in Drug Development:
POLYADENYLIC ACID (5') POTASSIUM SALT is used as a target for small molecule mRNA in the development of therapeutic agents. It is employed to evaluate the binding of potential therapeutic agents, such as the Isoquinoline group of alkaloids, which can modulate mRNA function and have potential applications in treating various diseases.
Used in Diagnostic Assays:
Poly(A) is used in droplet digital PCR (ddPCR) assay, a highly sensitive and accurate method for detecting and quantifying nucleic acids. It serves as a carrier for the amplification and detection of specific DNA or RNA sequences, enabling precise measurement of target molecules in various biological samples.
Used in Nucleic Acid Precipitation:
POLYADENYLIC ACID (5') POTASSIUM SALT is used as a carrier for the quantitative precipitation of DNA and RNA. It binds to nucleic acids through electrostatic interactions, facilitating their precipitation and separation from other cellular components. This property makes Poly(A) a valuable tool in nucleic acid purification, isolation, and analysis.
Biochem/physiol Actions
Polyadenylic acid (Poly(A)) tails present at 3′ end are produced in the cell nucleus. It contains ~250 nucleotides in mammalian cells.?Poly(A) regulates mRNA decay and the initiation of translation. Cytoplasmic poly(A) extension modulates translation.
Check Digit Verification of cas no
The CAS Registry Mumber 26763-19-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,7,6 and 3 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 26763-19:
(7*2)+(6*6)+(5*7)+(4*6)+(3*3)+(2*1)+(1*9)=129
129 % 10 = 9
So 26763-19-9 is a valid CAS Registry Number.