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Cas Database

267643-79-8

267643-79-8

267643-79-8

Identification

Synonyms:(3S)-1-(2-phenylethyl)pyrrolidin-3-amine

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Chemical Properties

Safety information and MSDS

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  • Manufacture/Brand:Acrotein
  • Product Description:(3S)-1-(2-Phenylethyl)-3-pyrrolidinamine 97%
  • Packaging:0.5g
  • Price:$ 440
  • Delivery:In stock
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  • Manufacture/Brand:ACHEMBLOCK
  • Product Description:(3S)-1-(2-Phenylethyl)-3-pyrrolidinamine 95%
  • Packaging:250MG
  • Price:$ 385
  • Delivery:In stock
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  • Manufacture/Brand:ACHEMBLOCK
  • Product Description:(3S)-1-(2-Phenylethyl)-3-pyrrolidinamine 95%
  • Packaging:100MG
  • Price:$ 185
  • Delivery:In stock
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Relevant articles and documentsAll total 2 Articles be found

2-PHENYL-3H-IMIDAZO[4,5-B]PYRIDINE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN TYROSINE KINASE ROR1 ACTIVITY

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Page/Page column 96-97, (2016/09/22)

A compound of formula (I′) or (I′′) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of mammalian kinase enzyme activity, including ROR1 tyrosine kinase activity and may be used in the treatment of disorders associated with such activity.

Process route upstream and downstream products

Process route

tert-butyl [(3S)-1-(2-phenylethyl)pyrrolidin-3-yl]carbamate

tert-butyl [(3S)-1-(2-phenylethyl)pyrrolidin-3-yl]carbamate

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine
267643-79-8,876165-17-2

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine

Conditions
Conditions Yield
With hydrogenchloride; In 1,4-dioxane; water; at 20 ℃; for 3h;
92%
(3S)-1-(2-phenylethyl)pyrrolidin-3-amine
267643-79-8,876165-17-2

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine

Conditions
Conditions Yield
8-azabicyclo[3.2.1]octane
280-05-7

8-azabicyclo[3.2.1]octane

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine
267643-79-8,876165-17-2

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-8-azabicyclo[3.2.1]octane-8-carboxamide

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-8-azabicyclo[3.2.1]octane-8-carboxamide

Conditions
Conditions Yield
diethyl cyanophosphonate
2942-58-7

diethyl cyanophosphonate

2,2-diphenylacetic acid
117-34-0

2,2-diphenylacetic acid

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine
267643-79-8,876165-17-2

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)diphenylacetamide
267643-80-1

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)diphenylacetamide

Conditions
Conditions Yield
With triethylamine; In ethyl acetate; N,N-dimethyl-formamide;
9-Thioxanthenylcarboxylic acid
17394-14-8

9-Thioxanthenylcarboxylic acid

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine
267643-79-8,876165-17-2

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-9-thioxanthenylcarboxamide

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-9-thioxanthenylcarboxamide

Conditions
Conditions Yield
quinuclidin-3-amine
76883-48-2,120570-05-0,123536-15-2,6238-14-8,781591-76-2

quinuclidin-3-amine

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine
267643-79-8,876165-17-2

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine

1-(quinuclidin-3-yl)-3-((S)-1-(2-phenylethyl)pyrrolidin-3-yl)urea
1392473-70-9

1-(quinuclidin-3-yl)-3-((S)-1-(2-phenylethyl)pyrrolidin-3-yl)urea

Conditions
Conditions Yield
xanthene-9-carboxylic acid
82-07-5

xanthene-9-carboxylic acid

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine
267643-79-8,876165-17-2

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-9-xanthenylcarboxamide

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-9-xanthenylcarboxamide

Conditions
Conditions Yield
1-Azabicyclo[2.2.2]octane-4-carbonyl chloride
98948-50-6

1-Azabicyclo[2.2.2]octane-4-carbonyl chloride

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine
267643-79-8,876165-17-2

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-1-azabicyclo[2.2.2]octane-4-carboxamide
1392473-52-7

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-1-azabicyclo[2.2.2]octane-4-carboxamide

Conditions
Conditions Yield
9,10-dihydroanthracene-9-carboxylic acid
1143-20-0

9,10-dihydroanthracene-9-carboxylic acid

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine
267643-79-8,876165-17-2

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-9,10-dihydroanthracene-9-carboxamide

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-9,10-dihydroanthracene-9-carboxamide

Conditions
Conditions Yield
1,4-Diazatricyclo[4.3.1.1(3,8)]undecane
1258933-04-8

1,4-Diazatricyclo[4.3.1.1(3,8)]undecane

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine
267643-79-8,876165-17-2

(3S)-1-(2-phenylethyl)pyrrolidin-3-amine

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-1,4-diazatricyclo[4.3.1.1(3,8)]undecane-4-carboxamide

(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-1,4-diazatricyclo[4.3.1.1(3,8)]undecane-4-carboxamide

Conditions
Conditions Yield

267643-79-8 Downstream products

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  • NovaChemistry
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