267646-06-0Relevant articles and documents
Rapid synthesis of triazine inhibitors of inosine monophosphate dehydrogenase.
Pitts, William J,Guo, Junqing,Dhar, T G Murali,Shen, Zhongqi,Gu, Henry H,Watterson, Scott H,Bednarz, Mark S,Chen, Bang Chi,Barrish, Joel C,Bassolino, Donna,Cheney, Daniel,Fleener, Catherine A,Rouleau, Katherine A,Hollenbaugh, Diane L,Iwanowicz, Edwin J
, p. 2137 - 2140 (2007/10/03)
A series of novel triazine-based small molecule inhibitors (IV) of inosine monophosphate dehydrogenase was prepared. The synthesis and the structure-activity relationships (SAR) derived from in vitro studies are described.