26850-26-0

Basic information

• Product Name: 2-[(4-hydroxyphenyl)amino]-2-methylpropanenitrile
• CAS NO: 26850-26-0
• Molecular Formula: C₁₀H₁₂N₂O
• Molecular Weight: 176.2151
• Mol File: 26850-26-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 378.4°C at 760 mmHg
• Flash Point: 182.7°C
• Density: 1.172g/cm³
• Vapor Pressure: 2.89E-06mmHg at 25°C
• Refractive Index: 1.601
• CAS DataBase Reference: 2-[(4-hydroxyphenyl)amino]-2-methylpropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(4-hydroxyphenyl)amino]-2-methylpropanenitrile(26850-26-0)
• EPA Substance Registry System: 2-[(4-hydroxyphenyl)amino]-2-methylpropanenitrile(26850-26-0)

Safety Data

• Hazardous Substances Data: 26850-26-0(Hazardous Substances Data)

Usage

General Description

2-[(4-hydroxyphenyl)amino]-2-methylpropanenitrile is a chemical compound with the molecular formula C10H12N2O. It is also known as 4-hydroxyphenyl-alpha,alpha-dimethylamino-nitrile and is commonly used in the pharmaceutical industry as a building block or intermediate in the synthesis of various drugs. 2-[(4-hydroxyphenyl)amino]-2-methylpropanenitrile is a nitrile, which means it contains a cyano group (–C≡N) and a hydroxyl group (–OH) attached to a benzene ring. It is important to handle this chemical with care, as it can be potentially hazardous if not used properly.

Upstream product

• 123-30-8 4-amino-phenol 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 151-50-8 potassium cyanide 
• 67-64-1 acetone 
• 7677-24-9 trimethylsilyl cyanide 
• 51-78-5 p-aminophenol hydrochloride 

Downstream Products

• 951753-40-5 5-[3-(4-hydroxyphenyl)-4,4-dimethyl-5-oxo-2-sulfanylideneimidazolidin-1-yl]-3-(trifluoromethyl)pyridine-2-carbonitrile 
• 915086-32-7 4-[3-(4-hydroxyphenyl)-4,4-dimethyl-5-oxo-2-sulfanylideneimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile 
• 80824-77-7 4'-(benzyloxy)benzanilide 

Relevant articles and documents

SUBSTITUTED 3-((3-AMINOPHENYL)AMINO)PIPERIDINE-2,6-DIONE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

Provided herein are piperidine dione compounds having the following structure (I) wherein RN, R1, R2, R3, R4, L,V, m, and n are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.

IMIDAZOLINE DERIVATIVES, PREPARATION METHODS THEREOF, AND THEIR APPLICATIONS IN MEDICINE

New imidazoline derivatives represented by formula (I): preparation methods thereof, pharmaceutical compositions comprising such derivatives, and applications of such derivatives in preparing androgen receptor antagonists and medicaments for treating diseases such as prostate cancer are described.

DIARYLHYDANTOIN COMPOUNDS

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