27060-75-9

Basic information

• Product Name: 2-Bromo-5-methoxytoluene
• Synonyms: 2-Bromo-5-methoxytoluene, 1-Bromo-4-methoxy-2-methylbenzene, 4-Bromo-3-methylphenyl methyl ether;2-BroMo-5-Methoxytoluene (BMA);4-BroMo-3-Methylanisole, 97%, 97%;2-Bromo-4-methoxy-1-methylbenzene;1-BROMO-4-METHOXY-2-METHYLBENZENE;2-BROMO-5-METHOXYTOLUENE;3-Methyl-4-bromoanisole;4-BROMO-3-METHYLANISOLE
• CAS NO: 27060-75-9
• Molecular Formula: C₈H₉BrO
• Molecular Weight: 201.06
• Product Categories: Aromatic Hydrocarbons (substituted) & Derivatives;Halogen toluene;Anisoles, Alkyloxy Compounds & Phenylacetates;Bromine Compounds
• Mol File: 27060-75-9.mol
• Article Data: 47

Chemical Properties

• Melting Point: 16.5 °C
• Boiling Point: 111-112 °C15 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: Clear colorless to slightly yellow/Liquid
• Density: 1.424 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0773mmHg at 25°C
• Refractive Index: n20/D 1.561(lit.)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: water: soluble (Partially miscible)(lit.)
• BRN: 1933865
• CAS DataBase Reference: 2-Bromo-5-methoxytoluene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-5-methoxytoluene(27060-75-9)
• EPA Substance Registry System: 2-Bromo-5-methoxytoluene(27060-75-9)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 27060-75-9(Hazardous Substances Data)

Usage

Chemical Properties

colorless to light yellow liquid

InChI:InChI=1/C8H9BrO/c1-6-5-7(10-2)3-4-8(6)9/h3-5H,1-2H3

Upstream product

• 14472-14-1 4-bromo-3-methylphenol 
• 74-88-4 methyl iodide 
• 100-84-5 1-methoxy-3-methyl-benzene 
• 52289-55-1 (4-methoxy-2-methylphenyl)methanol 
• 6245-57-4 4-methoxy-2-methylbenzoic acid 
• 128-08-5 N-Bromosuccinimide 
• 76006-33-2 3-bromo-2-methylbenzoic acid 
• 121-43-7 Trimethyl borate 
• 5367-32-8 5-methoxy-2-nitrotoluene 
• 108-39-4 3-methyl-phenol 
• 59554-30-2 5-methoxy-toluene-2-sulfonic acid 
• 7732-18-5 water 
• 7726-95-6 bromine 
• 60-29-7 diethyl ether 

Downstream Products

• 63121-53-9 p-Methoxy-o-tolyldi-tert.-butylcarbinol 
• 10126-37-1 (2-bromo-5-methoxyphenyl)-N,N-dimethylmethanamine 
• 521958-77-0 2-(4-methoxy-2-methylphenyl)-pyridine 
• 20940-84-5 1,2,3-Trimethyl-3-(2-methoxy-4-methyl-5-bromphenyl)-cyclopenten 
• 23963-92-0 2,3-Dimethyl-3-(2-methoxy-4-methyl-5-bromphenyl)-cyclopenten 
• 23963-90-8 2-<2-Methoxy-4-methyl-5-brom-phenyl>-cyclopentanon 
• 23963-91-9 2-Methyl-2-<2-methoxy-4-methyl-5-brom-phenyl>-cyclopentanon 
• 23964-01-4 1,2,5-Trimethyl-2-<2-methoxy-4-methyl-5-brom-phenyl>-cyclopentanol 
• 74562-16-6 2,5-Dimethyl-2-<2-methoxy-4-methyl-5-brom-phenyl>-cyclopentanon 
• 23964-04-7 2,3-Dimethyl-3-(2-hydroxy-4-methyl-5-bromphenyl)-cyclopenten 
• 23960-10-3 1,3,3-Trimethyl-2-(2-hydroxy-4-methyl-5-bromphenyl)-cyclopenten 
• 23963-93-1 3,3-Dimethyl-2-<2-methoxy-4-methyl-5-brom-phenyl>-cyclopentanon 
• 23963-96-4 3,4-Dimethyl-3-<2-methoxy-4-methyl-5-brom-phenyl>-cyclopentenon-(5) 
• 23964-10-5 2-Chlor-2,3-dimethyl-3-<2-methoxy-4-methyl-5-brom-phenyl>-cyclopentanon 

Relevant articles and documents

Visible light-induced mono-bromination of arenes with BrCCl3

A highly efficient and regioselective bromination of electron-rich arenes and heteroarenes using commercially available BrCCl3as a “Br” source has been developed. The reaction was performed in air under mild conditions with photocatalyst Ru(bpy)3Cl2·6H2O, avoiding the usage of strong acids and strong oxidants. Mono-brominated products were obtained with medium to excellent yields (up to 94%). This strategy has shown good compatibility and highpara-selectivity, which will facilitate the complicated synthesis.

Micro reaction system and method for synthesizing 4-bromo-3-methylanisole through two-phase method

The invention discloses a micro reaction system and method for synthesizing 4-bromo-3-methylanisole through a two-phase method, and belongs to the technical field of chemical engineering. The micro reaction system comprises a micro mixer, a micro packed b

Transition-metal-free decarboxylative bromination of aromatic carboxylic acids

Methods for the conversion of aliphatic acids to alkyl halides have progressed significantly over the past century, however, the analogous decarboxylative bromination of aromatic acids has remained a longstanding challenge. The development of efficient methods for the synthesis of aryl bromides is of great importance as they are versatile reagents in synthesis and are present in many functional molecules. Herein we report a transition metal-free decarboxylative bromination of aromatic acids. The reaction is applicable to many electron-rich aromatic and heteroaromatic acids which have previously proved poor substrates for Hunsdiecker-type reactions. In addition, our preliminary mechanistic study suggests that radical intermediates are not involved in this reaction, which is in contrast to classical Hunsdiecker-type reactivity. Overall, the process demonstrates a useful method for producing valuable reagents from inexpensive and abundant starting materials.