27171-30-8

Basic information

• Product Name: N-benzyl-N-isopropyl-2,3-epoxypropylamine
• Synonyms: N-benzyl-N-isopropyl-2,3-epoxypropylamine
• CAS NO: 27171-30-8
• Molecular Weight: 205.3
• Mol File: 27171-30-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl-N-isopropyl-2,3-epoxypropylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-N-isopropyl-2,3-epoxypropylamine(27171-30-8)
• EPA Substance Registry System: N-benzyl-N-isopropyl-2,3-epoxypropylamine(27171-30-8)

Safety Data

• Hazardous Substances Data: 27171-30-8(Hazardous Substances Data)

Upstream product

• 102-97-6 Benzyl-isopropyl-amin 
• 247033-00-7 N-benzyl-N-isopropylallylamine 
• 106-89-8 epichlorohydrin 

Downstream Products

• 50456-34-3 1-amino-3-(benzyl-isopropyl-amino)-propan-2-ol 
• 7695-63-8 (+/-)-1-isopropylamino-3-phenoxypropan-2-ol 
• 53729-51-4 (S)-1-(benzyl-isopropyl-amino)-3-(naphthalen-1-yloxy)propan-2-ol 
• 247033-02-9 (S)-1-(Benzyl-isopropyl-amino)-3-(2-methoxy-phenoxy)-propan-2-ol 
• 105183-42-4 Acetic acid (R)-1-acetoxymethyl-2-(benzyl-isopropyl-amino)-ethyl ester 
• 77164-20-6 (2S)-1-(isopropylamino)-3-(2-methoxyphenoxy)propan-2-ol 
• 4199-09-1 (S)-1-isopropylamino-3-(1-naphthyloxy)-2-propanol 
• 105183-41-3 (R)-3-(Benzyl-isopropyl-amino)-propane-1,2-diol 
• 247033-01-8 (S)-N-benzyl-N-isopropyl-2,3-epoxypropylamine 
• 22820-39-9 (+/-)-1-(N-benzyl)isopropylamino-3-phenoxypropan-2-ol 

Relevant articles and documents

Synthesis of novel and enantiomerically pure epoxypropylamine: A divergent route to the chiral β-adrenergic blocking agents

The chiral building block (S)-N-benzyl-N-isopropyl-2,3-epoxypropylamine is obtained by means of chlorohydroxylation of allylamine, followed by Jacobsen's hydrolytic kinetic resolution with water. A concise, divergent five-step synthesis of three β-adrenergic blocking agents in high enantiomeric excess using (S)-N-benzyl-N-isopropyl-2,3-epoxypropylamine as the key intermediate is described.