27305-49-3

Basic information

• Product Name: 1-oxo-1,5-naphthyridin-1-ium-5(1H)-olate
• Synonyms: 1,5-Naphthyridine 1,5-dioxide
• CAS NO: 27305-49-3
• Molecular Formula: C₈H₆N₂O₂
• Molecular Weight: 162.1454
• Mol File: 27305-49-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-oxo-1,5-naphthyridin-1-ium-5(1H)-olate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-oxo-1,5-naphthyridin-1-ium-5(1H)-olate(27305-49-3)
• EPA Substance Registry System: 1-oxo-1,5-naphthyridin-1-ium-5(1H)-olate(27305-49-3)

Safety Data

• Hazardous Substances Data: 27305-49-3(Hazardous Substances Data)

Usage

General Description

1-oxo-1,5-naphthyridin-1-ium-5(1H)-olate is a chemical compound with a complex and specific structure. It belongs to the class of naphthyridine derivatives, which have various biological and pharmacological activities. 1-oxo-1,5-naphthyridin-1-ium-5(1H)-olate contains a naphthyridine ring system with a nitrogen atom and an oxygen atom, giving it unique chemical and physical properties. It is commonly used in medicinal chemistry and drug development as it exhibits potential therapeutic effects, particularly in the treatment of various diseases and disorders. Its precise structure and functional groups make it a valuable molecule for further research and potential applications in the fields of medicine, pharmaceuticals, and biotechnology.

Upstream product

• 254-79-5 1,5-naphthyridine 
• 79-21-0 peracetic acid 
• 64-19-7 acetic acid 
• 462-08-8 pyridin-3-ylamine 
• 7722-84-1 dihydrogen peroxide 

Downstream Products

• 27017-66-9 2,6-dichloro-1,5-naphthyridine 
• 27017-70-5 1,5-dihydro-1,5-naphthyridine-2,6-dione 

Relevant articles and documents

Linear-shaped thermally activated delayed fluorescence emitter using 1,5-naphthyridine as an electron acceptor for efficient light extraction

In this study, we developed a donor-π-acceptor-π-donor-type thermally activated delayed fluorescence (TADF) emitter (NyDPAc) using 1,5-naphthyridine as a core moiety. NyDPAc exhibited a high horizontal dipole ratio and thus a high external quantum efficiency (20.9%) even at a relatively low photoluminescence quantum yield (57%). 1,5-naphthyridine as an electron acceptor represents a promising core moiety for efficient TADF materials.

Discovery of N-(Pyridin-4-yl)-1,5-naphthyridin-2-amines as Potential Tau Pathology PET Tracers for Alzheimer’s Disease

A mini-HTS on 4000 compounds selected using 2D fragment-based similarity and 3D pharmacophoric and shape similarity to known selective tau aggregate binders identified N-(6-methylpyridin-2-yl)quinolin-2-amine 10 as a novel potent binder to human AD aggreg