2741-13-1

Basic information

• Product Name: 1,1-dimethyl-3-(4-methylphenyl)thiourea
• Synonyms: 1,1-Dimethyl-3-(4-methylphenyl)thiourea; methanethiol, 1-(dimethylamino)-1-[(4-methylphenyl)imino]-, (Z)-; N,N-Dimethyl-N'-(4-methylphenyl)carbamimidothioic acid; thiourea, N,N-dimethyl-N'-(4-methylphenyl)-
• CAS NO: 2741-13-1
• Molecular Formula: C₁₀H₁₄N₂S
• Molecular Weight: 194.2966
• Mol File: 2741-13-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 271.5°C at 760 mmHg
• Flash Point: 118°C
• Density: 1.14g/cm³
• Vapor Pressure: 0.00644mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: 1,1-dimethyl-3-(4-methylphenyl)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethyl-3-(4-methylphenyl)thiourea(2741-13-1)
• EPA Substance Registry System: 1,1-dimethyl-3-(4-methylphenyl)thiourea(2741-13-1)

Safety Data

• Hazardous Substances Data: 2741-13-1(Hazardous Substances Data)

Usage

General Description

1,1-dimethyl-3-(4-methylphenyl)thiourea is a chemical compound with the molecular formula C10H14N2S. It is a thiourea derivative, which is a class of organic compounds containing a sulfhydryl group attached to a nitrogen atom. This specific compound consists of a central thiourea unit with two methyl groups and a 4-methylphenyl group attached to it. It is often used as a reagent in organic synthesis and has been studied for its potential antimicrobial, antifungal, and antitumor activities. Additionally, it has been used in the formulation of pharmaceuticals and dyes. This chemical has potential applications in various fields and is of interest for further research and development.

Upstream product

• 124-40-3 dimethyl amine 
• 622-59-3 1-isothiocyanato-4-methylbenzene 
• 137-26-8 Thiram 
• 106-49-0 p-toluidine 
• 16906-70-0 phenyl N,N-dimethyl dithiocarbamate 

Downstream Products

• 75104-97-1 N,N,6-trimethylbenzo[d]thiazol-2-amine 
• 75592-13-1 C₁₁H₁₄N₄ 
• 74376-27-5 ethyl 5-methyl-2-p-tolylimino-1,3-oxathiole-4-carboxylate 
• 20044-34-2 ethyl 2-p-tolylimino-4-methyl-Δ⁴-thiazoline-5-carboxylate 
• 622-59-3 1-isothiocyanato-4-methylbenzene 
• 621-01-2 N,N'-Bis(p-tolyl)thiourea 
• 506-59-2 N,N-dimethylammonium chloride 
• 1329429-63-1 1,1-dimethyl-2-phenyl-3-p-tolyl-isothiourea 
• 1329429-61-9 N,N-dimethyl-2-phenylsulfanyl-N'-p-tolyl-benzamidine 
• 39192-94-4 N-(p-methylphenyl)-p-methoxybenzamide 
• 6917-08-4 N-(4-methylphenyl)-4-nitrobenzamide 
• 2447-95-2 4-chloro-N-(4-tolyl)benzamide 
• 6876-66-0 4,4'-dimethylbenzanilide 
• 582-78-5 N-(4-methylphenyl)benzamide 

Relevant articles and documents

Method for preparing aryl isothiourea

The invention discloses a method for preparing aryl isothiourea, wherein hydride is suspended in a solvent, and thiourea is sequentially added. O diiodo benzene followed by reaction to prepare aryl isothiosemicarbazone. The isothiourea structure is widely

Insertion of arynes into thioureas: A new amidine synthesis

Arynes, generated from trimethylsilyl phenyltriflate precursors, have been found to react with thioureas via a formal π-insertion into the C=S bond. The reaction contrasts with that of ureas, which proceeds via benzyne σ-insertion into the C-N bond, and r

Reaction of 1,4,2-Dithiazolium Salts with Amino Compounds

Systematic studies on the behavior of 1,4,2-dithiazolium cations (1) toward various amino compounds (ammonia, aliphatic and aromatic amines, hydrazine, semicarbazide, thiosemicarbazide derivatives, etc.) were performed.The reaction pathway could be classified into three types depending on possibile three fission modes of the initially-formed adduct.The main products were 5-imino-1,4,2-dithiazole, thiourea, and 1,3,4-thiadiazole derivatives, through the three different pathways, respectively.In order to clarify the factors controlling the reaction courses, the reactions of 1 with p-substituted aniline derivatives were carried out under systematically varying conditions.The strength of bases and the polaritiy of solvents had clear influence on the reactivity.The reaction mechanism is also discussed.