2757-92-8Relevant articles and documents
Ag-Cu copromoted direct C2-H bond thiolation of azoles with Bunte salts as sulfur sources
Du, Xiao,Hu, Yuntao,Wang, Rui,Wei, Yingsu,Xu, Hongyan,Zhang, Ying,Zhao, Huaiqing
supporting information, p. 5899 - 5904 (2021/07/12)
A direct C2-H thiolation of azoles with Bunte salts was achieved under the combined action of copper and silver salts. This protocol could furnish various substituted 2-thioazoles in moderate to good yields. This method has a broad substrate scope and shows good functional group tolerance.
A novel synthesis of 2-alkylthiobenzothiazoles and 2-alkylthiobenzoxazoles
Yu, Yanfei,Li, Zhengning,Jiang, Lan
experimental part, p. 632 - 640 (2012/06/01)
3H-Benzothiazole-2-thione and 3H-benzoxazole-2-thione were selectively S-alkylated by use of O-alkylisoureas as the alkylating reagents. The reactions could be performed under mild reaction conditions in short reaction times, and high yields were obtained using O-primary-alkylisoureas, whereas low yields were obtained with sec-and tert-alkylisoureas.
Thermal reactions of β-hydroxysulfides bearing benzothiazole: Sulfenic acid trapping via a spiro intermediate
Yamada, Nobuhiko,Koyasu, Takanori,Sonami, Mayumi,Aoi, Michiko,Tashiro, Shintaro,Sheikh, Md. Chanmiya,Ishida, Yusuke,Kawashima, Wataru,Yoshimura, Toshiaki,Morita, Hiroyuki
experimental part, p. 1142 - 1153 (2010/08/21)
Benzothiazolyl 2-hydroxyethyl sulfoxide (1a) was found to afford bis[2-(2-oxobenzotiazolyl)-ethyl] disulfide (2a) in the presence of DBU at rt. 2a was formed by the condensation of corresponding sulfenic acid intermediate. Thermolyses of 1a in the presence of ethyl propiolate at 60-140C were carried out to succeed to trap sulfenic acid 6a as an intermediate. Trapping of 2-benzothiazolyloxyenthanesulfenic acid (6a) revealed that the thermal reaction proceeded via a five-membered spiro intermediate 5a. Copyright Taylor & Francis Group.