279-27-6

Basic information

• Product Name: 1-azabicyclo[2.2.1]heptane
• Synonyms: 1-Azanorbornane;3-azabicyclo[2.2.1]heptane;1-azabicyclo[2.2.1]heptane
• CAS NO: 279-27-6
• Molecular Formula: C₆H₁₁N
• Molecular Weight: 97.15824
• EINECS: 205-997-8
• Mol File: 279-27-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 71 °C
• Boiling Point: 122.77°C at 760 mmHg
• Flash Point: 19.488°C
• Appearance: /
• Density: 0.999g/cm³
• Vapor Pressure: 13.734mmHg at 25°C
• Refractive Index: 1.521
• PKA: 11.12±0.20(Predicted)
• CAS DataBase Reference: 1-azabicyclo[2.2.1]heptane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-azabicyclo[2.2.1]heptane(279-27-6)
• EPA Substance Registry System: 1-azabicyclo[2.2.1]heptane(279-27-6)

Safety Data

• Hazardous Substances Data: 279-27-6(Hazardous Substances Data)

Usage

Type of compound

bicyclic organic compound

Nitrogen atom

saturated bridgehead

State at room temperature

colorless liquid

Uses

commonly used as a precursor in the synthesis of various chemical compounds

Structure

fairly rigid and compact

Applications

useful in the design of pharmaceuticals, agrochemicals, and other specialty chemicals; used as a building block in the production of polymers and as a solvent in certain organic reactions; potential applications in the field of materials science

Additional

used as a strain energy benchmark in organic chemistry studies

InChI:InChI=1/C6H11N/c1-3-7-4-2-6(1)5-7/h6H,1-5H2

Upstream product

• 55-22-1 pyridine-4-carboxylic acid 
• 855232-39-2 4-bromo-2-(2-bromo-ethyl)-butylamine 
• 53378-73-7 3-(Bromomethyl)-1,5-dibromopentane 
• 173936-20-4 1-azabicyclo[2.2.1]heptan-3-one oxime 
• 7732-18-5 water 
• 65920-56-1 4-(bromomethyl)piperidine hydrobromide 
• 6457-49-4 4-piperidinemethanol 
• 586-95-8 pyridine-4-methanol 
• 96835-17-5 ethyl tetrahydro-2H-pyran-4-carboxylate 
• 14774-37-9 (tetrahydro-2H-pyran-4-yl)methanol 
• 1570-45-2 isonicotinic acid ethylester 
• 1126-09-6 4-carbethoxypiperidine 
• 498-94-2 isonipecotic acid 

Downstream Products

• 108-89-4 picoline 
• 13669-28-8 1-methyl-4-methylene-1-azacyclohexane 

Relevant articles and documents

ELECTROLYTE, ELECTROLYTIC SOLUTION, AND ELECTROCHEMICAL DEVICE USING THE SAME

Disclosed herein is an electrolyte having excellent long-term reliability, a high withstanding voltage (a wide potential window), and high conductivity. The electrolyte contains a quaternary ammonium salt represented by the following general formula (1): wherein R1 represents a hydrocarbon group; R2 represents a hydrocarbon group, a hydrogen atom, or a halogen atom; R3 to R14 each represent an alkyl group, a fluoroalkyl group, a hydrogen atom or a halogen atom, C and C* each represent a carbon atom, N represents a nitrogen atom; h, i, j, x, y, and z are each an integer of 0 to 6, (h+x) is an integer of 0 to 6, (i+y) and (j+z) are each an integer of 1 to 6; and X? represents a counter anion having a HOMO energy of ?0.60 to ?0.20 a.u. as determined by the first-principle calculation on molecular orbital of the counter anion.

SPIRO-ISOXAZOLIDINE DERIVATIVES AS CHOLINERGIC AGENTS

Compounds of general formula I, STR1 wherein: A represents (CH. sub.2) m optionally substituted by R 3,B represents (CH. sub.2) n optionally substituted by R 4, R. sub.1 represents hydrogen, C 1-C 6 alkyl, C 1-6 alkenyl or C 1-6 alkynyl, R 2 represents hydrogen, C 1-C 6 alkyl or COOR 5, in which R 5 represents C 1-C 6 alkyl,R 3 and R. sub.4 independently represent hydrogen or C 1-C 6 alkyl, in addition, any two of R. sub.2, R 3 and R 4 may together form a C 1-3 alkylene chain,n and m independently represent an integer from 1-3 inclusive,Y represents O or S,and pharmaceutically acceptable acid addition salts thereof are useful as pharmaceuticals, in particular as central muscarinic acetylcholine receptor agonists. The compounds are therefore useful in the treatment of diseases such as presenile and senile dementia, Huntington's chorea, tardive dyskinesia, hyperkinesia, mania and Tourette Syndrome.