279256-99-4Relevant articles and documents
Divergent reaction pathways in amine additions to β-lactone electrophiles. An application to β-peptide synthesis
Nelson, Scott G.,Spencer, Keith L.,Cheung, Wing S.,Mamie, Steven J.
, p. 7081 - 7091 (2007/10/03)
β-Lactone electrophiles are subject to regioselective addition-elimination (AE) or SN2 ring opening with various nitrogen-based nucleophiles. Primary and secondary amines promote AE ring opening to deliver products that are the functional equiv