28034-80-2

Basic information

• Product Name: homoesperetin-7-O-rutinoside
• Synonyms: homoesperetin-7-O-rutinoside
• CAS NO: 28034-80-2
• Molecular Weight: 624.596
• Mol File: 28034-80-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: homoesperetin-7-O-rutinoside(CAS DataBase Reference)
• NIST Chemistry Reference: homoesperetin-7-O-rutinoside(28034-80-2)
• EPA Substance Registry System: homoesperetin-7-O-rutinoside(28034-80-2)

Safety Data

• Hazardous Substances Data: 28034-80-2(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 520-26-3 hesperidin 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 1420071-83-5 7-butoxy-2-(3,4-dimethoxyphenyl)-5-hydroxychroman-4-one 
• 4250-76-4 3’,4’-dimethyleriodictyol 

Relevant articles and documents

Synthesis and anti-hyperglycemic activity of hesperidin derivatives

A series of hesperidin derivatives were prepared and identified by IR, 1H NMR, and MS spectra. These compounds were evaluated in vitro and in vivo based on α-glucosidase inhibition, glucose consumption of HepG2 cells, and blood glucose level in streptozotocin-induced diabetic mice. The results revealed that all the compounds exhibited anti-hyperglycemic activities. The inhibition at 10-3 M of compounds 3 and 7a on α-glucosidase were 55.02% and 53.34%, respectively, as compared to 54.80% by acarbose. Treated by compound 3 and the reference drug metformin, glucose consumption of HepG2 cell were 1.78 and 2.11 mM, respectively. After the streptozotocin-induced diabetic mice were oral administrated with compound 3 at 100 mg kg-1 d-1 for 10 days, the blood glucose level of 3 treated mice (13.23 mM, P 0.05) showed significant difference when compared to model control (23.03 mM). Thus, compound 3 exhibited promising anti-hyperglycemic activity.