28314-82-1

Basic information

• Product Name: 4-bromo-2,5-difluorobenzoic acid
• Synonyms: 4-bromo-2,5-difluorobenzoic acid;Benzoic acid, 4-broMo-2,5-difluoro-;2,5-Difluoro-4-broMobenzoic acid
• CAS NO: 28314-82-1
• Molecular Formula: C₇H₃BrF₂O₂
• Molecular Weight: 236.9983264
• Mol File: 28314-82-1.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 285.0±40.0 °C(Predicted)
• Appearance: /
• Density: 1.872±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.70±0.10(Predicted)
• CAS DataBase Reference: 4-bromo-2,5-difluorobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2,5-difluorobenzoic acid(28314-82-1)
• EPA Substance Registry System: 4-bromo-2,5-difluorobenzoic acid(28314-82-1)

Safety Data

• Hazardous Substances Data: 28314-82-1(Hazardous Substances Data)

Usage

General Description

4-Bromo-2,5-difluorobenzoic acid is a type of aromatic halogen compound with several distinct chemical properties. As its name suggests, it contains both bromine (bromo) and fluorine (fluoro) components. Its molecular formula is C7H3BrF2O2. 4-bromo-2,5-difluorobenzoic acid exhibits acid properties due to the presence of a carboxyl group (-COOH). The presence of both bromine and fluorine in the benzoic acid structure can greatly affect the compound's reactivity and influence its potential uses in the field of organic synthesis. The unique combination of these halogens provides opportunities for varied interactions with other chemical entities. 4-bromo-2,5-difluorobenzoic acid falls under the category of research chemicals, frequently used in laboratories, but is not typically found within everyday consumer products. Concerning its physical properties, it appears as a crystalline solid under room conditions.

Upstream product

• 124-38-9 carbon dioxide 
• 327-51-5 1,4-dibromo-2,5-difluorobenzene 
• 1621165-11-4 tert-butyl 4-bromo-2,5-difluorobenzoate 

Downstream Products

• 123942-09-6 4-bromo-2,5-difluorobenzoic acid chloride 
• 1193162-21-8 4-bromo-2,5-difluoro-benzoic acid methyl ester 
• 1621165-14-7 2,5-difluoro-4-formyl-N-methylbenzamide 
• 1621165-13-6 4-cyano-2,5-difluoro-N-methylbenzamide 
• 1621165-12-5 4-bromo-2,5-difluoro-N-methylbenzamide 
• 1780187-45-2 4-bromo-5-fluoro-2-methoxybenzoic acid 

Relevant articles and documents

ANTIBACTERIAL COMPOUNDS AND NEW USES THEREOF

This invention relates to a series of compounds of formula (I) for use in treating infections caused by obligate anaerobic bacteria, including Clostridium difficile, and to methods of treating said infections by administering said compounds. The compounds can be used against strains of obligate anaerobic bacteria that have developed resistance to other antibiotics. Many compounds used in the invention contain a tricyclic ring system.

In vitro and in vivo identification of novel positive allosteric modulators of the human dopamine D2 and D3 receptor

Agonists at dopamine D2 and D3 receptors are important therapeutic agents in the treatment of Parkinson's disease. Compared with the use of agonists, allosteric potentiators offer potential advantages such as temporal, regional, and phasic potentiation of

CARBAZOLE DERIVATIVES

Disclosed are compounds of Formula (I): (I) or a salt thereof, wherein Q, R1a, R1b, R2a, R2b, R3, R4, R5a, R5b, R6a, R6c, R7a, R7b, R7c, and R7d are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.