2873-74-7

Basic information

• Product Name: GLUTARYL DICHLORIDE
• Synonyms: GLUTARYL CHLORIDE;GLUTARYL DICHLORIDE;1,3-PROPANEDICARBONYL CHLORIDE;1,3-Bis(Chlorocarbonyl)propane;Glutaric acid dichloride;glutaricaciddichloride;Glutaroyl chloride;glutaroylchloride
• CAS NO: 2873-74-7
• Molecular Formula: C₅H₆Cl₂O₂
• Molecular Weight: 169.01
• EINECS: 220-711-1
• Product Categories: Acid Halides;Carbonyl Compounds;Organic Building Blocks;Acid Halides;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 2873-74-7.mol
• Article Data: 31

Chemical Properties

• Boiling Point: 216-218 °C(lit.)
• Flash Point: 224 °F
• Appearance: Clear colorless to yellow or red-brownish/Liquid
• Density: 1.324 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.13mmHg at 25°C
• Refractive Index: n20/D 1.472(lit.)
• Sensitive: Moisture Sensitive
• BRN: 1363191
• CAS DataBase Reference: GLUTARYL DICHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: GLUTARYL DICHLORIDE(2873-74-7)
• EPA Substance Registry System: GLUTARYL DICHLORIDE(2873-74-7)

Safety Data

• Hazard Codes: C
• Statements: 22-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2922 8/PG 3
• WGK Germany: 3
• RTECS: SA2583000
• F: 10-21
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 2873-74-7(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR COLORLESS TO YELLOW OR RED-BROWNISH LIQUID

InChI:InChI=1/C5H6Cl2O2/c6-4(8)2-1-3-5(7)9/h1-3H2

Upstream product

• 108-55-4 glutaric anhydride, 
• 110-94-1 1,5-pentanedioic acid 
• 124-04-9 Adipic acid 
• 110-15-6 succinic acid 
• 544-13-8 Glutaronitrile 
• 111-29-5 1 ,5-pentanediol 
• 7719-09-7 thionyl chloride 

Downstream Products

• 4609-11-4 1,5-bis(4-methoxyphenyl)pentane-1,5-dione 
• 252190-10-6 1,5-bis-[6-O-(n-butyl-2,3,4-tri-O-benzyl-α-glucopyranoside)] glutarate 
• 113614-98-5 glutaric acid bis-(2,4-dinitrophenylhydrazide) 
• 56932-04-8 1,4-dihydroxy-2,3-dimethyl-7,8-dihydrobenzocycloheptene-5,9-(6H)-dione 
• 139658-13-2 (2R,4aR,6S,6aR,13aS,13bR)-6-Methoxy-2-phenyl-octahydro-1,3,5,7,13-pentaoxa-cyclonona[a]naphthalene-8,12-dione 
• 139658-12-1 C₃₈H₄₄O₁₆ 
• 139658-11-0 (2R,4aR,6S,6aR,13aS,13bR,15R,17aR,19S,19aR,26aS,26bR)-6,19-Dimethoxy-2,15-diphenyl-hexadecahydro-1,3,5,7,13,14,16,18,20,26-decaoxa-cyclooctadeca[1,2-a;10,11-a']dinaphthalene-8,12,21,25-tetraone 
• 139658-14-3 Pentanedioic acid bis-((2R,4aR,6S,7R,8S,8aS)-8-hydroxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl) ester 
• 139658-16-5 Pentanedioic acid (2R,4aR,6S,7R,8S,8aR)-6-methoxy-7-(4-methoxycarbonyl-butyryloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester methyl ester 
• 89959-35-3 Pentanedioic acid bis-[(4-chloro-phenyl)-hydroxy-amide] 
• 10365-74-9 1.3-Bis(2-hydroxy-5-methoxybenzoyl)propane 
• 89959-33-1 Pentanedioic acid bis-(hydroxy-o-tolyl-amide) 
• 5768-13-8 N-phenylglutarimide 
• 121014-14-0 1,2-Bis(4-methylphenyl)perhydro-3,7-diazepindion 

Relevant articles and documents

Construction of the A/B/C core of mexicanolides via a tandem double-aldol reaction

An efficient and concise approach for rapid assembly of the ABC tricyclic carbon skeleton of mexicanolide-type limonoids is described. The acetal/ketal diketoester precursors were prepared from simple starting materials by LiOH-mediated Michael reactions. The ABC tricyclic skeleton bearing multiple stereogenic centers was efficiently constructed by a powerful one-pot cascade reaction, which includes acetal/ketal hydrolysis, double intramolecular aldol condensation, and alkene migration.

Aziridine-2-carboxylic acid derivatives and its open-ring isomers as a novel PDIA1 inhibitors

[Figure not available: see fulltext.] Acyl derivatives of aziridine-2-carboxylic acid have been synthesized and tested as PDIA1 inhibitors. Calculations of charge value and distribution in aziridine ring system and some alkylating agents were performed. For the first time was found that acyl derivatives of aziridine-2-carboxylic acid are weak to moderately active PDIA1 inhibitors.

SUBSTITUTED HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY

The present invention relates to certain heterocyclic compounds of Formula (I) that have the ability to inhibit lysine biosynthesis via the diaminopimelate biosynthesis pathway in certain organisms. As a result of this activity these compounds can be used in applications where inhibition of lysine biosynthesis is useful. Applications of this type include the use of the compounds as herbicides. Formula (I)