28748-19-8Relevant articles and documents
Ru(II)-Catalyzed Chemoselective C(sp3)-H Monoarylation of 8-Methyl Quinolines with Arylboronic Acids
Parmar, Diksha,Kumar, Rohit,Kumar, Rakesh,Sharma, Upendra
, p. 11844 - 11855 (2020/10/23)
The transition-metal-promoted C-H activation has become an efficient as well as atom-economic methodology for the synthesis of a wide array of organic molecules, but the cost of the metal catalyst and selectivity remain the major challenges. Herein, the first [Cl2Ru(p-cymene)]2-catalyzed direct monoarylation of unactivated C(sp3)-H bonds of 8-methyl quinolines with arylboronic acids to synthesize diarylmethane compounds is presented. The transformation shows a broad substrate scope with high chemoselectivity for the synthesis of 8-benzyl quinolines. In the preliminary mechanistic studies, control experiments, deuterium labeling experiments, and kinetic studies have been performed.
Pd-Catalyzed Alkylation of (Iso)quinolines and Arenes: 2-Acylpyridine Compounds as Alkylation Reagents
Wu, Qingsong,Han, Shuaijun,Ren, Xiaoxiao,Lu, Hongtao,Li, Jingya,Zou, Dapeng,Wu, Yangjie,Wu, Yusheng
, p. 6345 - 6348 (2018/10/20)
The first Pd-catalyzed alkylation of (iso)quinolines and arenes is reported. The readily available and bench-stable 2-acylpyridine compounds were used as an alkylation reagent to form the structurally versatile alkylated (iso)quinolines and arenes. The method affords a convenient pathway for the introduction of alkyl groups into organic molecules.
Chelation-assisted palladium-catalyzed acyloxylation of benzyl sp3 C-H bonds using PhI(OAc)2 as oxidant
Zhang, Shouhui,Luo, Fang,Wang, Wenhui,Jia, Xiaofei,Hu, Maolin,Cheng, Jiang
supporting information; experimental part, p. 3317 - 3319 (2010/07/10)
A chelation-assisted palladium-catalyzed acyloxylation of the sp3 C-H bond of benzyl by carboxylic acid is described, which employs PhI(OAc)2 as a stoichiometric oxidant. The procedure tolerates a series of functional groups, such as
