2926-29-6

Basic information

• Product Name: Sodium trifluoromethanesulfinate
• Synonyms: SODIUM TRIFLUOROMETHANESULPHINATE;SODIUM TRIFLUOROMETHANESULFINATE;TRIFLUOROMETHANESULFINIC ACID SODIUM SALT;Trifluoromethanesulphinic acid, sodium salt;Methanesulfinic acid,1,1,1-trifluoro-, sodiuM salt;SodiuM Triflinate;Langlois reagent;Sodium trifluoromethylsulfinate
• CAS NO: 2926-29-6
• Molecular Formula: CF₃O₂S*Na
• Molecular Weight: 156.06
• Mol File: 2926-29-6.mol
• Article Data: 9

Chemical Properties

• Melting Point: <325°C
• Boiling Point: 222.8 °C at 760 mmHg
• Flash Point: 88.5 °C
• Appearance: /
• Vapor Pressure: 0.0369mmHg at 25°C
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: Water (Sparingly)
• BRN: 3723394
• CAS DataBase Reference: Sodium trifluoromethanesulfinate(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium trifluoromethanesulfinate(2926-29-6)
• EPA Substance Registry System: Sodium trifluoromethanesulfinate(2926-29-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-36/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• TSCA: No
• HazardClass: IRRITANT
• Hazardous Substances Data: 2926-29-6(Hazardous Substances Data)

Usage

Chemical Properties

White to light yellow solid

Uses

Different sources of media describe the Uses of 2926-29-6 differently. You can refer to the following data:
1. Efficient sulfinate salt for the trifluoromethylation of various aryls, aryl boronic acids, alkenes, and alkynes.
2. Sodium Triflinate, is a sulfur-containing building block and Fluorination reagents, used in various organic synthesis. It can be used in a new and convenient method for the copper-catalyzed construction of functional sulfonamides in good yields and excellent chemoselectivity.

InChI:InChI=1/CHF3O2S.Na/c2-1(3,4)7(5)6;/h(H,5,6);/q;+1/p-1

Upstream product

• 421-83-0 trifluoromethane sulfonyl chloride 
• 335-05-7 Trifluoromethanesulfonyl fluoride 
• 34642-42-7 trifluoromethanesulfinic acid 
• 2712-93-8 dichlorofluoromethanesulphenyl chloride 
• 155201-03-9 ethyl 3-(trifluoromethanesulfonyl)propionate 
• 52208-98-7 [1-(trifluoromethylsulfonyl)ethane-1,2-diyl]dibenzene 
• 75-72-9 chlorotrifluoromethane 
• 81325-99-7 Trifluormethansulfinsaeure-Azid 
• 75-63-8 Bromotrifluoromethane 

Downstream Products

• 107264-08-4 N-Fluoro-2,6-bis(methoxycarbonyl)pyridinium triflate 
• 60933-15-5 phenyl trifluoromethanethiosulfonate 
• 2314-97-8 iodotrifluoromethane 
• 120067-83-6 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile 
• 20621-29-8 trifluoromethylsulfinyl chloride 
• 405074-85-3 (2,3,4,5,6-pentafluorophenyl)methyl trifluoromethyl sulfone 
• 1947-95-1 (2,4-dichloro-phenyl)-trifluoromethyl sulfoxide 
• 2189-43-7 p-tolyl trifluoromethyl sulfoxide 
• 708-67-8 4-aminophenyl trifluoromethylsulfoxide 
• 1948-04-5 N-(4-((trifluoromethyl)sulfinyl)phenyl)acetamide 
• 223683-77-0 1-trifluoromethanesulfinyl-4-trifluoromethoxy-benzene 
• 223683-76-9 1,5-dibromo-3-methyl-2-trifluoromethanesulfinyl-benzene 
• 223683-75-8 2,4-difluoro-1-trifluoromethanesulfinyl-benzene 
• 129265-01-6 (3,3,3-Trifluoro-1-methoxy-propylsulfanyl)-benzene 

Relevant articles and documents

Reactions of Bromotrifluoromethane and Related Halides. 8. Condensations with Dithionite and Hydroxymethanesulfinate Salts

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PROCESS FOR THE PREPARATION OF FIPRONIL AND ANALOGUES THEREOF

The present invention relates to a new and efficient process for preparing 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-IH-pyrazole-3-carbonitrile (hereinafter referred to as compound of formula I), which is useful as an intermediate for the antiparasitic agent fipronil, and a process for preparing 5-amino-3-cyano-l-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethyl sulfinylpyrazole (hereinafter referred to as compound of formula II or fipronil). In one aspect, there is provided a process for preparing fipronil comprising: a) a step of reacting CF3S(=O)ONa with the compound of formula (III) in the presence of a reducing/halogenating agent; and b) a step of oxidizing the compound of formula (I) obtained in step a) in the presence of a selective oxidizing agent, under suitable conditions, wherein the selective oxidizing agent selectively effects oxidation of (I) to the corresponding sulfoxide, Fipronil. In certain exemplary embodiments, the selective oxidizing agent is MHSO5, wherein M is an alkaline metal cation.

A new preparation of trifluoromethanesulfinate salts

Trifluoromethanesulfinate (triflinate) salts can be prepared in an ecofriendly way by β-elimination of aliphatic triflones bearing an acidic hydrogen in β position. This technique allows the synthesis of various triflinate salts under mild conditions.