2934-07-8

Basic information

• Product Name: 2,4,6-triisopropylphenol
• Synonyms: 2,4,6-triisopropylphenol;2,4,6-Tris(1-methylethyl)phenol;Ai3-11243;Einecs 220-907-7;Phenol, 2,4,6-tris(1-methylethyl)-
• CAS NO: 2934-07-8
• Molecular Formula: C₁₅H₂₄O
• Molecular Weight: 220.35046
• EINECS: 220-907-7
• Mol File: 2934-07-8.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 274.4°Cat760mmHg
• Flash Point: 123.3°C
• Appearance: /
• Density: 0.925g/cm³
• Vapor Pressure: 0.00324mmHg at 25°C
• Refractive Index: 1.505
• CAS DataBase Reference: 2,4,6-triisopropylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-triisopropylphenol(2934-07-8)
• EPA Substance Registry System: 2,4,6-triisopropylphenol(2934-07-8)

Safety Data

• Hazardous Substances Data: 2934-07-8(Hazardous Substances Data)

Usage

General Description

2,4,6-triisopropylphenol is a chemical compound with the molecular formula C18H26O. It is a colorless to light yellow liquid that is insoluble in water and has a characteristic aromatic odor. This chemical is used as an antioxidant, stabilizer, and UV absorber in various industrial and consumer products, including plastics, polymers, fuels, and cosmetics. It is also known for its antimicrobial properties, making it a common ingredient in personal care products and disinfectants. However, 2,4,6-triisopropylphenol is considered harmful if ingested or inhaled and may cause irritation to the skin and eyes, so proper handling and storage are important when using this chemical.

InChI:InChI=1/C15H24O/c1-9(2)12-7-13(10(3)4)15(16)14(8-12)11(5)6/h7-11,16H,1-6H3

Upstream product

• 187737-37-7 propene 
• 7637-07-2 boron trifluoride 
• 108-95-2 phenol 
• 94-71-3 2-Ethoxyphenol 
• 64-17-5 ethanol 
• 120-80-9 benzene-1,2-diol 
• 90-05-1 2-methoxy-phenol 
• 150-76-5 4-methoxy-phenol 
• 67-63-0 isopropyl alcohol 
• 108894-99-1 (2,4,6-triisopropylphenyl)magnesium bromide 
• 1447973-69-4 C₂₃H₂₈O₄ 
• 717-74-8 1,3,5-triisopropyl benzene 
• 7601-90-3 perchloric acid 
• 7664-39-3 hydrogen fluoride 

Downstream Products

• 88-69-7 2-(1-methylethyl)phenol 
• 2934-05-6 2,4-diisopropylphenol 
• 2078-54-8 2,6-diisopropylphenol 
• 14753-96-9 [2,4,6-tris(1-methylethyl)phenoxy]acetic acid 
• 64532-94-1 isopropyl diphenyl phosphate 
• 55864-04-5 diphenyl-p-isopropylphenyl phosphate 
• 96107-55-0 2,4-diisopropylphenyl diphenyl phosphate 
• 177793-76-9 ethyl (2,4,6-triisopropylphenoxysulfonyl)acetate 

Relevant articles and documents

Arene oxidation with malonoyl peroxides

Malonoyl peroxide 7, prepared in a single step from the commercially available diacid, is an effective reagent for the oxidation of aromatics. Reaction of an arene with peroxide 7 at room temperature leads to the corresponding protected phenol which can be unmasked by aminolysis. An ionic mechanism consistent with the experimental findings and supported by isotopic labeling, Hammett analysis, EPR investigations, and reactivity profile studies is proposed.

Synthesis of phenols and aryl silyl ethers via arylation of complementary hydroxide surrogates

Two transition-metal-free methods to access substituted phenols via the arylation of silanols or hydrogen peroxide with diaryliodonium salts are presented. The complementary reactivity of the two nucleophiles allows synthesis of a broad range of phenols without competing aryne formation, as illustrated by the synthesis of the anesthetic Propofol. Furthermore, silyl-protected phenols can easily be obtained, which are suitable for further transformations.

Synthesis and catalytic performance of HMCM-49/MCM-41 composite molecular sieve for alkylation of phenol with isopropanol

HMCM-49/MCM-41 composite molecular sieve was synthesized with hydrothermal method. The physicochemical properties of the composite were characterized by using XRD, FT-IR, SEM, N2 isothermal adsorption-desorption and NH3-TPD. Results of different characterizations indicated that the synthesized composite molecular sieve possessed the characteristics of both HMCM-49 and MCM-41. XRD and N2 isothermal adsorption-desorption revealed that it has both micropores and mesopores, a larger surface area than that of HMCM-49, NH3-TPD and pyridine adsorbed FT-IR revealed that the strong acidic sites that caused side reaction in HMCM-49 are deactivated in the composite molecular sieve of HMCM-49/MCM-41. When applied to the alkylation of phenol with isopropanol, the HMCM-49/MCM-41 composite molecular sieve exhibit an enhanced catalytic performance with significant enhancement in p-isopropylphenol and o-isopropylphenol selectivity, which can be ascribed to the composite characteristics of HMCM-49 and MCM-41. This kind of material will has widely industrial application in preparation of alkyl-phenol.