293752-49-5

Basic information

• Product Name: (1R,2R) 2-hydroxy-cyclohexyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranoside
• Synonyms: (1R,2R) 2-hydroxy-cyclohexyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranoside
• CAS NO: 293752-49-5
• Molecular Weight: 694.735
• Mol File: 293752-49-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R) 2-hydroxy-cyclohexyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R) 2-hydroxy-cyclohexyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranoside(293752-49-5)
• EPA Substance Registry System: (1R,2R) 2-hydroxy-cyclohexyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranoside(293752-49-5)

Safety Data

• Hazardous Substances Data: 293752-49-5(Hazardous Substances Data)

Upstream product

• 1072-86-2 (1R,2R)-trans-1,2-cyclohexanediol 
• 203435-09-0 2,3,4,6-tetra-O-benzoyl-α,b-D-galactopyranosyl trichloroacetimidate 

Downstream Products

• 293752-50-8 (1R,2R) 2-hydroxy-cyclohexyl 3-O-[2-O-(5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosonate)]-β-D-galactopyranoside 
• 294677-28-4 (1R,2R) 2-hydroxy-cyclohexyl β-D-galactopyranoside 

Relevant articles and documents

Substrate specificity of fucosyl transferase III: An efficient synthesis of sialyl Lewis(x) -, sialyl Lewis(a)- derivatives and mimetics thereof

Fucosyl transferase III (FucT III) has previously been characterized as the most general enzyme of the FucT family, as judged from its ability to catalyze the transfer of fucose to both Galβ(1-3)GlcNAc and Galβ(1-4)GlcNAc. In order to explore the synthetic potential of FucT III for the enzymatic synthesis of sialyl Lewis(x) and sialyl Lewis(a) derivatives, its substrate specificity has been probed using a number of natural substrate mimetics. A remarkable range of acceptor substrates was found when N-acetyl glucosamine was replaced by D-glucal, (R,R)-1,2-cyclohexanediol and (R,R)-butan-2,3-diol. Although the reaction rates were low compared to the reaction with the natural substrates, they proved to be sufficient for the synthesis of preparative amounts.