294193-58-1

Basic information

• Product Name: (E)-4-((4-cyanophenyl)amino)-4-oxobut-2-enoic acid
• Synonyms: (E)-4-((4-cyanophenyl)amino)-4-oxobut-2-enoic acid;4-[(4-cyanophenyl)amino]-4-oxo-2-butenoic acid;(2E)-4-[(4-cyanophenyl)amino]-4-oxobut-2-enoic acid;4-(4-cyanoanilino)-4-oxo-2-butenoic acid
• CAS NO: 294193-58-1
• Molecular Formula: C11H8N2O3
• Molecular Weight: 216.19282
• Mol File: 294193-58-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-4-((4-cyanophenyl)amino)-4-oxobut-2-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-((4-cyanophenyl)amino)-4-oxobut-2-enoic acid(294193-58-1)
• EPA Substance Registry System: (E)-4-((4-cyanophenyl)amino)-4-oxobut-2-enoic acid(294193-58-1)

Safety Data

• Hazardous Substances Data: 294193-58-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Development:
(E)-4-((4-cyanophenyl)amino)-4-oxobut-2-enoic acid is used as an intermediate in the synthesis of various pharmaceuticals for its diverse reactivity and properties. It contributes to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Development:
In the agrochemical industry, (E)-4-((4-cyanophenyl)amino)-4-oxobut-2-enoic acid is used as a building block for the creation of new agrochemicals, potentially enhancing crop protection and yield.
Used as an Antiseptic:
(E)-4-((4-cyanophenyl)amino)-4-oxobut-2-enoic acid, under the trade name Acriflavine, is used as an antiseptic due to its antimicrobial properties, helping to prevent infection in various medical settings.
Used as a Disinfectant:
Similarly, Acriflavine is utilized as a disinfectant to eliminate harmful microorganisms from surfaces, contributing to improved hygiene and reduced risk of disease transmission.
Used in Anticancer Research:
(E)-4-((4-cyanophenyl)amino)-4-oxobut-2-enoic acid is a subject of interest in the medical and scientific communities for its potential anti-cancer properties. It may be used in the development of novel cancer treatments, targeting various types of cancer cells.
Used in Antimicrobial Applications:
(E)-4-((4-cyanophenyl)amino)-4-oxobut-2-enoic acid's potential antimicrobial properties make it a candidate for use in the development of new antimicrobial agents, which could be applied in various industries, including healthcare and agriculture, to combat microbial infections.

Upstream product

• 108-31-6 maleic anhydride 
• 873-74-5 4-Aminobenzonitrile 

Relevant articles and documents

The synthesis of (Z)-4-oxo-4-(arylamino)but-2-enoic acids derivatives and determination of their inhibition properties against human carbonic anhydrase I and II isoenzymes

The synthesis of (Z)-4-oxo-4-(arylamino)but-2-enoic acid (4) derivatives containing structural characteristics that can be used for the synthesis of several active molecules, is presented. Some of the butenoic acid derivatives (4a, 4c, 4e, 4i, 4j, 4k) are

Radical-mediated dehydrative preparation of cyclic imides using (NH4)2S2O8-DMSO: Application to the synthesis of vernakalant

Ammonium persulfate-dimethyl sulfoxide (APS-DMSO) has been developed as an efficient and new dehydrating reagent for a convenient one-pot process for the synthesis of miscellaneous cyclic imides in high yields starting from readily available primary amines and cyclic anhydrides. A plausible radical mechanism involving DMSO has been proposed. The application of this facile one-pot imide forming process has been demonstrated for a practical synthesis of vernakalant.

Synthesis and copolymerization study of new polyimide precursors with potential application in optical and photonic field

New polyimide precursors were synthesized by simple one step procedure. (Z)-3-(4-Nitro-phenylcarbamoyl)-acrylic acid (A2), (Z)-3-(4-Ciano- phenylcarbamoyl)-acrylic acid (A3), (Z)-3-(4-Diethyl-phenylcarbamoyl)-acrylic acid (A4) and (Z)-3-[N'-(2,4-Dinitro-phenyl)-hydrazinocarbonyl]-acrylic acid (A6) were characterized by FT-IR, FT-NMR and UV-VIS spectroscopy. Test copolymerization successfully yielded copolymers that were characterized by FT-IR and FT-NMR spectroscopy. Improved solubility of these copolymers make them candidates for potential NLO applications.

INFLUENCE OF MEDIUM AND SUBSTITUENTS ON ACYLATION OF AROMATIC AMINES AND THEIR POLYMERIC ANALOGS WITH MALEIC ANHYDRIDE

Correlation relationships describing the influence of substituents and solvents on the rate of acylation of aromatic amines and their polymeric analogs with maleic anhydride have been derived.