2964-79-6Relevant articles and documents
Aerial oxidation of the glucocorticoid side-chain under pH control
Edmonds, John S.,Morita, Masatoshi,Turner, Peter,Skelton, Brian W.,White, Allan H.
, p. 34 - 41 (2007/10/03)
The outcome of aerial oxidation of the glucocortico-steroid side-chain (as exemplified by dexamethasone) has been shown to be subject to strict pH control. At pH 7.4 the glyoxal is the only product; at pH values of 8 and 9.2 the etioacid is formed, and at
General method for determination of configuration of steroid-17-yL methyl glycolates at C-20
Suzuki,Tada,Matsuda,Yang,Unno
, p. 1481 - 1483 (2007/10/02)
Kinetic examination for methoxycarbonylations of the isomeric steroid-17- yl methyl glycolates at C-20 and plots of the amount of each isomer produced by a reaction of their corresponding steroids with cupric acetate in absolute methanol provide a general and facile method for determination of the configuration of the steroid-17-yl methyl glycolates at C-20.
Novel pregnanoic acid derivatives
-
, (2008/06/13)
Pregnanoic acid derivatives of general formula STR1 wherein is a single bond or a double bond; X is hydrogen, fluorine or methyl; Y is hydrogen, fluorine or chlorine; Z is β-hydroxymethylene, β-acyloxymethylene, β-fluoromethylene, β-chloromethylene, carbonyl or methylene; R1 is hydrogen, methyl in the α- or β-position or methylene and R2 is hydrogen, hydroxy or acyloxy, or R1 and R2 collectively are alkylidendioxy and U1 is halogen, halogenated alkyl of 1-5 carbon atoms or halogenated phenyl, are topically effective anti-inflammatory agents.
