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29648-66-6

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29648-66-6 Usage

General Description

4-Methylenecyclohexanone, also known as piperonyl ketone, is a chemical compound with the molecular formula C8H12O. It is a colorless liquid with a strong, floral odor that is commonly used as a flavoring agent in the food industry. It is also used as a precursor in the synthesis of fragrances and pharmaceuticals. Additionally, 4-Methylenecyclohexanone is a key intermediate in the production of piperonylmethyl ketone, which is used in the manufacture of amphetamine and methamphetamine. The compound is flammable and should be handled with care, as it poses a risk of fire and explosion. Overall, 4-Methylenecyclohexanone has important applications in the food, fragrance, and pharmaceutical industries, but its handling requires strict safety measures.

Check Digit Verification of cas no

The CAS Registry Mumber 29648-66-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,6,4 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 29648-66:
(7*2)+(6*9)+(5*6)+(4*4)+(3*8)+(2*6)+(1*6)=156
156 % 10 = 6
So 29648-66-6 is a valid CAS Registry Number.

29648-66-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-methylidenecyclohexan-1-one

1.2 Other means of identification

Product number -
Other names Cyclohexanone,4-methylidene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:29648-66-6 SDS

29648-66-6Downstream Products

29648-66-6Relevant articles and documents

CYCLIC BRIDGEHEAD ETHER DGAT1 INHIBITORS

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Paragraph 0402;0403; 0404, (2013/11/06)

The invention relates to compounds of formula (I): useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.

HYDROXY SUBSTITUTED ISOQUINOLINONE DERIVATIVES

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Page/Page column 158-159, (2013/02/28)

The invention relates to compounds of formula (I): as defined in the application. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof.

Design and synthesis of cell potent BACE-1 inhibitors: Structure-activity relationship of P1′ substituents

Sealy, Jennifer M.,Truong, Anh P.,Tso, Luke,Probst, Gary D.,Aquino, Jose,Hom, Roy K.,Jagodzinska, Barbara M.,Dressen, Darren,Wone, David W.G.,Brogley, Louis,John, Varghese,Tung, Jay S.,Pleiss, Michael A.,Tucker, John A.,Konradi, Andrei W.,Dappen, Michael S.,Toth, Gergely,Pan, Hu,Ruslim, Lany,Miller, Jim,Bova, Michael P.,Sinha, Sukanto,Quinn, Kevin P.,Sauer, John-Michael

scheme or table, p. 6386 - 6391 (2010/06/11)

Using structure-guided design, hydroxyethylamine BACE-1 inhibitors were optimized to nanomolar Aβ cellular inhibition with selectivity against cathepsin-D. X-ray crystallography illuminated the S1′ residues critical to this effort, which culminated in compounds 56 and 57 that exhibited potency and selectivity but poor permeability and high P-gp efflux.

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