29681-57-0

Basic information

• Product Name: T-BUTYLDIMETHYLSILANE
• Synonyms: T-BUTYLDIMETHYLSILANE;TERT-BUTYLDIMETHYLSILANE;Butyldimethylsilane;triethyl-propyl-silane;Dimethyl tert-butylsilane;tert-ButyldiMethylsilane 95%;tert-Butyldimethylsilane;Silane,(1,1-dimethylethyl)dimethyl-
• CAS NO: 29681-57-0
• Molecular Formula: C₆H₁₆Si
• Molecular Weight: 116.28
• Product Categories: Organometallic Reagents;Organosilicon;Others
• Mol File: 29681-57-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 13°C
• Boiling Point: 81-83 °C(lit.)
• Flash Point: −9 °F
• Appearance: /
• Density: 0.701 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.4(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• BRN: 2231162
• CAS DataBase Reference: T-BUTYLDIMETHYLSILANE(CAS DataBase Reference)
• NIST Chemistry Reference: T-BUTYLDIMETHYLSILANE(29681-57-0)
• EPA Substance Registry System: T-BUTYLDIMETHYLSILANE(29681-57-0)

Safety Data

• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 16-26-36-16/26/36
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• F: 10-21
• TSCA: Yes
• HazardClass: 3.1
• PackingGroup: I
• Hazardous Substances Data: 29681-57-0(Hazardous Substances Data)

Usage

General Description

T-Butyldimethylsilane, also known as tert-Butyldimethylsilane or TBDMS, is an organosilicon compound that is primarily used in the field of organic chemistry as a protecting agent. Its molecular formula is C6H16Si and its structure consists of a t-butyl group (C4H9) and two methyl groups (CH3), bonded to a silicon atom. This substance is colorless, has a mild smell, and is insoluble in water. It's used to protect reactive hydroxy, amine, or carboxy groups during chemical reactions, preventing them from unwanted participation and can be removed afterwards with ease under controlled conditions. Additionally, it plays a role in the manufacturing of certain pharmaceuticals and silicone-based products.

InChI:InChI=1/C6H15Si/c1-6(2,3)7(4)5/h1-5H3

Upstream product

• 1380397-69-2 Zn(Si(CH₃)2(C(CH₃)3))2 
• 62791-22-4 tert-butyl(cyclohex-1-en-1-yloxy)dimethylsilane 

Downstream Products

• 62791-22-4 tert-butyl(cyclohex-1-en-1-yloxy)dimethylsilane 
• 139391-04-1 3-[1-(tert-Butyl-dimethyl-silanyl)-meth-(Z)-ylidene]-1-(toluene-4-sulfonyl)-1-aza-spiro[3.5]nonan-2-one 
• 139372-17-1 {1-[(Z)-2-(tert-Butyl-dimethyl-silanyl)-1-formyl-vinyl]-cyclohexyl}-carbamic acid methyl ester 
• 139372-12-6 3-[1-(tert-Butyl-dimethyl-silanyl)-meth-(Z)-ylidene]-2-oxo-1-aza-spiro[3.5]nonane-1-carboxylic acid methyl ester 
• 139372-15-9 3-[1-(tert-Butyl-dimethyl-silanyl)-meth-(Z)-ylidene]-4-pentyl-1-(toluene-4-sulfonyl)-azetidin-2-one 
• 139372-18-2 N-{1-[(Z)-2-(tert-Butyl-dimethyl-silanyl)-1-formyl-vinyl]-hexyl}-4-methyl-benzenesulfonamide 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 92976-56-2 tert-butyldimethyl(1-phenylethoxy)silane 
• 18173-64-3 tert-butyldimethylsilanol 
• 53172-91-1 (benzyloxy)(tert-butyl)dimethylsilane 
• 150272-59-6 1-methyl-3-phenylpropyl tert-butyldimethylsilyl ether 
• 72726-45-5 tert-butyldimethylsilyl iodide 
• 53742-62-4 anilino(tert-butyldimethyl)silane 
• 67124-67-8 1-(tert-butyldimethylsiloxy)cyclohexane 

Relevant articles and documents

Activation of Homolytic Si-Zn and Si-Hg Bond Cleavage, Mediated by a Pt0 Complex, via Novel Pt-Zn and Pt-Hg Compounds

The thermally stable [(tBuMe2Si)2M] (M=Zn, Hg) generate R3Si. radicals in the presence of [(dmpe)Pt(PEt3)2] at 60-80 C. The reaction proceeds via hexacoordinate Pt complexes, (M=Zn (2 a and 2 b), M=Hg (3 a and 3 b)) which were isolated and characterized. Mild warming or photolysis of 2 or 3 lead to homolytic dissociation of the Pt-MSiR3 bond generating silyl radicals and novel unstable pentacoordinate platinum paramagnetic complexes (M=Zn (5), Hg (6)) whose structures were determined by EPR spectroscopy and DFT calculations. SiM City: The thermally stable [(tBuMe2Si)2M] (M=Zn, Hg) generate R3Si. radicals in the presence of [(dmpe)Pt(PEt3)2]. The enhancing effect of the Pt complex on the homolytic cleavage of the Si-M bonds in [(tBuMe2Si)2M] is mediated by formation of octahedral hexacoordinate Pt-M trinuclear complexes.