2990-52-5 Usage
Chemical class
Steroid compound Belongs to the androstane class of steroids, which are a group of naturally occurring and synthetic compounds with a specific carbon skeleton structure.
Derivative
Testosterone It is a derivative of testosterone, a naturally occurring hormone and primary male sex hormone.
Fluorine atom
16th position The presence of a fluorine atom at the 16th position in the molecule distinguishes it from other androstane steroids.
Keto group
17th position A keto group (C=O) is present at the 17th position, which contributes to the compound's chemical reactivity and properties.
Acetate group
3rd position An acetate group is attached to the 3rd position, which can influence the compound's solubility and reactivity.
Pharmaceutical research
Precursor It is commonly used as a precursor in the synthesis of various steroid-based drugs, making it valuable in the development of new medications.
Biological and pharmacological effects
Fluorinated steroids The structure and chemical properties of this compound make it suitable for investigating the effects of fluorinated steroids on biological systems.
Potential applications
Hormonal disorders and cancer Due to its unique structure, it may have potential applications in the development of new therapeutic agents for conditions such as hormonal disorders and certain types of cancers.
Molecular weight
Approximately 360 g/mol The molecular weight provides an estimate of the mass of one mole of the compound, which can be useful for determining concentrations and calculating reaction stoichiometry.
Solubility
Moderately soluble in organic solvents The compound is expected to have moderate solubility in organic solvents like ethanol, methanol, or acetone, which is important for its use in chemical synthesis and pharmaceutical formulations.
Stability
Stable under normal conditions The compound is generally stable under normal storage and handling conditions, which is essential for its use in research and pharmaceutical applications.
Reactivity
Reacts with nucleophiles and reducing agents Due to the presence of the keto group and the fluorine atom, the compound can undergo reactions with nucleophiles (e.g., amines, alcohols) and reducing agents (e.g., sodium borohydride), which can be exploited in the synthesis of related compounds.
Synthesis
Multi-step process The synthesis of 16-fluoro-17-oxoandrost-5-en-3-yl acetate typically involves a multi-step process, starting from testosterone and introducing the desired functional groups through various chemical reactions.
Structural analysis
NMR, IR, and mass spectrometry Techniques like nuclear magnetic resonance (NMR), infrared (IR) spectroscopy, and mass spectrometry are used to analyze and confirm the structure of the synthesized compound.
Purity
High-performance liquid chromatography (HPLC) HPLC is a common analytical technique used to determine the purity of the synthesized compound, ensuring that it meets the required standards for pharmaceutical research and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 2990-52-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,9 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2990-52:
(6*2)+(5*9)+(4*9)+(3*0)+(2*5)+(1*2)=105
105 % 10 = 5
So 2990-52-5 is a valid CAS Registry Number.
2990-52-5Relevant articles and documents
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Rozen,S.,Lerman,O.
, p. 2782 - 2784 (1979)
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N-Fluoropyridinium Pyridine Heptafluorodiborate: A Useful Fluorinating Agent
Poss, A. J.,Puy, M. Van Der,Nalewajek, D.,Shia, G. A.,Wagner, W. J.,Frenette, R. L.
, p. 5962 - 5964 (2007/10/02)
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TAMING ELEMENTAL FLUORINE: INDIRECT USE OF FLUORINE FOR THE SYNTHESIS OF α-FLUOROKETONES
Rozen Shlomo,Menahem, Ynon
, p. 19 - 32 (2007/10/02)
Fluorine and sodium trifloroacetate react at -75 deg to produce a variety of fluoroxy-compounds.Although it is possible to direct the reaction towards the formation of CF3COOF or CF3CF2O, mixtures may be used when only the electrophilic fluorine has to be
