300696-53-1Relevant articles and documents
Design, synthesis, and biological evaluation of new thieno[2,3-d] pyrimidine derivatives as targeted therapy for PI3K with molecular modelling study
Elmenier, Fatma M.,Lasheen, Deena S.,Abouzid, Khaled A. M.
, p. 315 - 332 (2022/01/04)
Cancer is one of the most aggressive diseases characterised by abnormal growth and uncontrolled cell division. PI3K is a lipid kinase involved in cancer progression which makes it fruitful target for cancer control. 28 new morpholine based thieno[2,3-d] p
Synthesis, antitumor and antibacterial activities of some novel tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives
Abbas, Safinaz E.,Abdel Gawad, Nagwa M.,George, Riham F.,Akar, Yahya A.
, p. 195 - 204 (2013/10/01)
Two series of new tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines namely 2,3-disubstituted derivatives 3a-z and 2,4-disubstituted ones 6a-c were prepared and tested for their antitumor and antibacterial activities. The structures of the prepared compounds we